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iShares Biotechnology ETF

955 hedge funds and large institutions have $6.94B invested in iShares Biotechnology ETF in 2025 Q4 according to their latest regulatory filings, with 215 funds opening new positions, 275 increasing their positions, 219 reducing their positions, and 44 closing their positions.

New
Increased
Maintained
Reduced
Closed

389% more first-time investments, than exits

New positions opened: 215 | Existing positions closed: 44

71% more funds holding in top 10

Funds holding in top 10: 712 (+5)

50% more capital invested

Capital invested by funds: $4.63B → $6.94B (+$2.31B)

26% more repeat investments, than reductions

Existing positions increased: 275 | Existing positions reduced: 219

19% more funds holding

Funds holding: 803955 (+152)

2.91% more ownership

Funds ownership: 80.08%82.98% (+2.9%)

1% less call options, than puts

Call options by funds: $257M | Put options by funds: $260M

Holders
955
Holders Change
+152
Holders Change %
+18.93%
% of All Funds
11.62%
Holding in Top 10
12
Holding in Top 10 Change
+5
Holding in Top 10 Change %
+71.43%
% of All Funds
0.15%
New
215
Increased
275
Reduced
219
Closed
44
Calls
$257M
Puts
$260M
Net Calls
-$3.01M
Net Calls Change
+$65.5M
Name Holding Trade Value Shares
Change
Change in
Stake
Bank of America
1
Bank of America
North Carolina
$1.11B +$107M +658,317 +11%
Citigroup
2
Citigroup
New York
$885M +$247M +1,521,992 +41%
Morgan Stanley
3
Morgan Stanley
New York
$541M +$12.5M +76,978 +2%
BNP Paribas Financial Markets
4
BNP Paribas Financial Markets
France
$360M +$35.4M +218,066 +11%
Two Sigma Investments
5
Two Sigma Investments
New York
$249M +$229M +1,409,300 +2,145%
Envestnet Asset Management
6
Envestnet Asset Management
Illinois
$206M +$190M +1,172,666 +2,327%
Goldman Sachs
7
Goldman Sachs
New York
$203M -$218M -1,343,824 -53%
Raymond James Financial
8
Raymond James Financial
Florida
$168M +$120M +736,881 +286%
LPL Financial
9
LPL Financial
California
$168M +$95.7M +589,033 +146%
UBS Group
10
UBS Group
Switzerland
$154M -$28.9M -178,014 -16%
CB
11
Commerce Bank
Missouri
$139M +$38.8M +238,768 +41%
Wells Fargo
12
Wells Fargo
California
$128M +$29.5M +181,345 +32%
Royal Bank of Canada
13
Royal Bank of Canada
Ontario, Canada
$123M +$26.8M +165,012 +29%
Barclays
14
Barclays
United Kingdom
$113M +$41.5M +255,750 +61%
Truist Financial
15
Truist Financial
North Carolina
$108M +$99.8M +614,582 +2,240%
WA
16
WestEnd Advisors
North Carolina
$106M +$102M +629,667 New
Janney Montgomery Scott
17
Janney Montgomery Scott
Pennsylvania
$105M +$95.5M +588,124 +1,871%
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
18
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$101M -$25M -154,000 -21%
JP Morgan Chase
19
JP Morgan Chase
New York
$58.7M -$116M -711,991 -67%
PNC Financial Services Group
20
PNC Financial Services Group
Pennsylvania
$54.8M +$3.01M +18,514 +6%
Susquehanna International Group
21
Susquehanna International Group
Pennsylvania
$51.3M +$35.6M +218,884 +257%
JFG
22
Jefferies Financial Group
New York
$50.7M -$24.4M -150,349 -33%
Victory Capital Management
23
Victory Capital Management
Texas
$37.7M +$36.3M +223,310 New
Thrivent Financial for Lutherans
24
Thrivent Financial for Lutherans
Minnesota
$37.6M +$18.1M +111,169 +99%
ACA
25
Aptus Capital Advisors
Alabama
$34.5M +$32.9M +202,269 +9,664%