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iShares Biotechnology ETF
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Overview Fund Activity

782 hedge funds and large institutions have $3.93B invested in iShares Biotechnology ETF in 2025 Q2 according to their latest regulatory filings, with 57 funds opening new positions, 136 increasing their positions, 342 reducing their positions, and 82 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
782
Holders Change
-39
Holders Change %
-4.75%
% of All Funds
10.49%
Holding in Top 10
7
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-12.5%
% of All Funds
0.09%
New
57
Increased
136
Reduced
342
Closed
82
Calls
$216M
Puts
$168M
Net Calls
+$47.6M
Net Calls Change
+$385M

Top Buyers

1
Goldman Sachs
1
Goldman Sachs
New York
$314M
2
Citigroup
2
Citigroup
New York
$515M
3
Morgan Stanley
3
Morgan Stanley
New York
$458M
4
JPMorgan Chase & Co
4
JPMorgan Chase & Co
New York
$105M
5
ERSOT
5
Employees Retirement System of Texas
Texas
$25M

Top Sellers

1
Bank of America
1
Bank of America
North Carolina
$776M
2
MMEA
2
Main Management ETF Advisors
California
$0
3
BNP Paribas Financial Markets
3
BNP Paribas Financial Markets
France
$58.6M
4
Barclays
4
Barclays
United Kingdom
$49.4M
5
Two Sigma Investments
5
Two Sigma Investments
New York
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
JWBC
151
J.W. Burns & Co
New York
$1.75M -$474K -3,745 -21%
NEPWA
152
New England Private Wealth Advisors
Massachusetts
$1.75M – – –
CTC
153
Central Trust Company
Missouri
$1.74M -$13.2K -104 -0.8%
AF
154
Apexium Financial
Texas
$1.72M -$390K -3,082 -18%
MFFIA
155
McIntyre, Freedman & Flynn Investment Advisers
Massachusetts
$1.7M – – –
WIP
156
WealthCare Investment Partners
Rhode Island
$1.68M +$120K +926 +8%
Fifth Third Bancorp
157
Fifth Third Bancorp
Ohio
$1.68M -$9.36K -74 -0.6%
MMA
158
Miracle Mile Advisors
California
$1.67M -$208K -1,642 -11%
AWM
159
Aprio Wealth Management
Georgia
$1.66M -$12.3M -96,985 -88%
IP
160
Intellectus Partners
California
$1.66M -$8.86K -70 -0.5%
EAM
161
Empirical Asset Management
Massachusetts
$1.65M -$67.8K -536 -4%
TYCC
162
Texas Yale Capital Corp
Florida
$1.62M -$404K -3,192 -20%
TFF
163
The Family Firm
Maryland
$1.62M +$56.3K +445 +4%
Fidelity Investments
164
Fidelity Investments
Massachusetts
$1.61M -$282K -2,231 -15%
ES
165
Eagle Strategies
New York
$1.55M -$71K -561 -4%
BA
166
Bellwether Advisors
Nebraska
$1.53M -$12.4K -98 -0.8%
RP
167
Raelipskie Partnership
Ontario, Canada
$1.52M -$123K -975 -7%
WB
168
WesBanco Bank
West Virginia
$1.47M – – –
LFS
169
Littlejohn Financial Services
Oregon
$1.46M +$1.46M +11,563 New
BRM
170
Boston Research & Management
Massachusetts
$1.45M -$58.4K -462 -4%
WLIM
171
White Lighthouse Investment Management
Massachusetts
$1.44M +$4.05K +32 +0.3%
AFO
172
Arrowroot Family Office
California
$1.43M +$1.43M +11,337 New
TCM
173
Telos Capital Management
California
$1.43M +$55.2K +436 +4%
GKWIM
174
Gerber Kawasaki Wealth & Investment Management
California
$1.43M -$1.16M -9,191 -45%
SF
175
Synovus Financial
Georgia
$1.39M +$21.1K +167 +2%
5 6
7
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