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iShares Biotechnology ETF
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Overview Fund Activity

782 hedge funds and large institutions have $3.93B invested in iShares Biotechnology ETF in 2025 Q2 according to their latest regulatory filings, with 57 funds opening new positions, 136 increasing their positions, 342 reducing their positions, and 82 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
782
Holders Change
-39
Holders Change %
-4.75%
% of All Funds
10.49%
Holding in Top 10
7
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-12.5%
% of All Funds
0.09%
New
57
Increased
136
Reduced
342
Closed
82
Calls
$216M
Puts
$168M
Net Calls
+$47.6M
Net Calls Change
+$385M

Top Buyers

1
Goldman Sachs
1
Goldman Sachs
New York
$314M
2
Citigroup
2
Citigroup
New York
$515M
3
Morgan Stanley
3
Morgan Stanley
New York
$458M
4
JPMorgan Chase & Co
4
JPMorgan Chase & Co
New York
$105M
5
ERSOT
5
Employees Retirement System of Texas
Texas
$25M

Top Sellers

1
Bank of America
1
Bank of America
North Carolina
$776M
2
MMEA
2
Main Management ETF Advisors
California
$0
3
BNP Paribas Financial Markets
3
BNP Paribas Financial Markets
France
$58.6M
4
Barclays
4
Barclays
United Kingdom
$49.4M
5
Two Sigma Investments
5
Two Sigma Investments
New York
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
BPAMU
126
BTG Pactual Asset Management US
New York
$1.98M +$54.8K +433 +3%
DC
127
Davenport & Co
Virginia
$1.98M +$110K +869 +6%
BHWM
128
Bar Harbor Wealth Management
New Hampshire
$1.97M +$34.9K +276 +2%
AWMNY
129
Arcadia Wealth Management (New York)
New York
$1.94M -$39.9K -315 -2%
CIA
130
Choate Investment Advisors
Massachusetts
$1.94M – – –
P
131
&Partners
Tennessee
$1.92M +$24.6K +195 +1%
Wolverine Trading
132
Wolverine Trading
Illinois
$1.91M +$1.91M +15,092 New
US Bancorp
133
US Bancorp
Minnesota
$1.91M -$17.2K -136 -0.9%
KIA
134
KCM Investment Advisors
California
$1.91M -$560K -4,430 -23%
MCP
135
Militia Capital Partners
Nevada
$1.9M +$1.9M +15,000 New
FWP
136
FAS Wealth Partners
Kansas
$1.89M -$445K -3,517 -19%
BCM
137
Brookstone Capital Management
Illinois
$1.87M +$857K +6,774 +84%
Mercer Global Advisors
138
Mercer Global Advisors
Colorado
$1.87M -$169K -1,333 -8%
MFG
139
Merit Financial Group
Georgia
$1.86M -$25.6K -202 -1%
VAS
140
Valicenti Advisory Services
New York
$1.86M -$48.1K -380 -3%
SG Americas Securities
141
SG Americas Securities
New York
$1.84M -$58.2K -460 -3%
CIP
142
Capital Insight Partners
Arizona
$1.83M -$221K -1,744 -11%
NA
143
NewEdge Advisors
Louisiana
$1.83M -$63.3K -500 -3%
Fidelity International
144
Fidelity International
Bermuda
$1.83M -$5.57K -44 -0.3%
CAG
145
Crestwood Advisors Group
Massachusetts
$1.82M -$165K -1,307 -8%
William Blair & Company
146
William Blair & Company
Illinois
$1.81M -$1.11M -8,799 -38%
Franklin Resources
147
Franklin Resources
California
$1.8M -$501K -3,958 -22%
MCA
148
Martin Capital Advisors
Texas
$1.79M – – –
1SB
149
1ST Source Bank
Indiana
$1.76M -$90.7K -717 -5%
PA
150
Pinnacle Associates
New York
$1.76M -$174K -1,379 -9%
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6
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