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iShares Biotechnology ETF
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Overview Fund Activity

781 hedge funds and large institutions have $3.93B invested in iShares Biotechnology ETF in 2025 Q2 according to their latest regulatory filings, with 57 funds opening new positions, 136 increasing their positions, 341 reducing their positions, and 82 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
781
Holders Change
-40
Holders Change %
-4.87%
% of All Funds
10.48%
Holding in Top 10
7
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-12.5%
% of All Funds
0.09%
New
57
Increased
136
Reduced
341
Closed
82
Calls
$216M
Puts
$168M
Net Calls
+$47.6M
Net Calls Change
+$385M

Top Buyers

1
Goldman Sachs
1
Goldman Sachs
New York
$314M
2
Citigroup
2
Citigroup
New York
$515M
3
Morgan Stanley
3
Morgan Stanley
New York
$458M
4
JPMorgan Chase & Co
4
JPMorgan Chase & Co
New York
$105M
5
ERSOT
5
Employees Retirement System of Texas
Texas
$25M

Top Sellers

1
Bank of America
1
Bank of America
North Carolina
$776M
2
MMEA
2
Main Management ETF Advisors
California
$0
3
BNP Paribas Financial Markets
3
BNP Paribas Financial Markets
France
$58.6M
4
Barclays
4
Barclays
United Kingdom
$49.4M
5
Two Sigma Investments
5
Two Sigma Investments
New York
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
Wellington Management Group
101
Wellington Management Group
Massachusetts
$2.7M +$2.7M +21,313 New
PCTC
102
Perkins Coie Trust Company
Washington
$2.67M -$189K -1,493 -7%
MWM
103
Marion Wealth Management
Pennsylvania
$2.66M +$106K +837 +4%
FFS
104
Fischer Financial Services
Pennsylvania
$2.65M -$86.3K -682 -3%
CIBC Private Wealth Group
105
CIBC Private Wealth Group
Georgia
$2.64M +$12K +95 +0.5%
MC
106
Martin & Co
Tennessee
$2.56M +$9.99K +79 +0.4%
CI
107
CAZ Investments
Texas
$2.53M +$1.18M +9,300 +87%
IA
108
IFP Advisors
Florida
$2.51M -$506 -4 -0%
Parallax Volatility Advisers
109
Parallax Volatility Advisers
California
$2.46M +$2.46M +19,413 +647,100%
KeyBank National Association
110
KeyBank National Association
Ohio
$2.41M -$39.3K -311 -2%
CAPTRUST Financial Advisors
111
CAPTRUST Financial Advisors
North Carolina
$2.37M +$331K +2,614 +16%
WIM
112
Westside Investment Management
California
$2.35M +$14.9K +118 +0.6%
Baird Financial Group
113
Baird Financial Group
Wisconsin
$2.3M -$888K -7,020 -28%
GC
114
Grimes & Company
Massachusetts
$2.3M +$2.3M +18,163 New
Northern Trust
115
Northern Trust
Illinois
$2.3M -$518K -4,091 -18%
AUB
116
Atlantic Union Bankshares
Virginia
$2.22M +$2.22M +17,541 New
GP
117
Greenline Partners
New York
$2.13M – – –
AI
118
ArchPoint Investors
Florida
$2.12M – – –
WA
119
Waverly Advisors
Alabama
$2.07M -$726K -5,742 -26%
BPCE
120
Bank Pictet & Cie (Europe)
Germany
$2.06M – – –
TCM
121
Traynor Capital Management
Pennsylvania
$2.03M -$763K -5,977 -27%
EH
122
Equitable Holdings
New York
$2.02M -$110K -872 -5%
Group One Trading
123
Group One Trading
Illinois
$2.02M +$2.02M +15,929 New
GRP
124
Global Retirement Partners
California
$2.01M +$2.01M +15,873 New
Comerica Bank
125
Comerica Bank
Texas
$2.01M -$70.5K -557 -3%
3 4
5
6 7