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iShares Biotechnology ETF
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Overview Fund Activity

821 hedge funds and large institutions have $3.97B invested in iShares Biotechnology ETF in 2025 Q1 according to their latest regulatory filings, with 49 funds opening new positions, 193 increasing their positions, 355 reducing their positions, and 78 closing their positions.

Holders
821
Holders Change
-44
Holders Change %
-5.09%
% of All Funds
11.15%
Holding in Top 10
8
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-27.27%
% of All Funds
0.11%
New
49
Increased
193
Reduced
355
Closed
78
Calls
$293M
Puts
$630M
Net Calls
-$338M
Net Calls Change
+$66.5M

Top Buyers

1
Citigroup
1
Citigroup
New York
$410M
2
UBS Group
2
UBS Group
Switzerland
$181M
3
Wells Fargo
3
Wells Fargo
California
$113M
4
JPMorgan Chase & Co
4
JPMorgan Chase & Co
New York
$61.2M
5
Squarepoint
5
Squarepoint
New York
$9.21M

Top Sellers

1
Jane Street
1
Jane Street
New York
$32.8M
2
Morgan Stanley
2
Morgan Stanley
New York
$359M
3
Bank of America
3
Bank of America
North Carolina
$891M
4
BNP Paribas Financial Markets
4
BNP Paribas Financial Markets
France
$117M
5
Royal Bank of Canada
5
Royal Bank of Canada
Ontario, Canada
$97.8M
Name Market Value Shares Shares
Change 		Shares
Change %
IAA
826
Independent Advisor Alliance
North Carolina
– – -51,196 Closed
WSCM
827
Wellington Shields Capital Management
New York
– – -39,663 Closed
Balyasny Asset Management
828
Balyasny Asset Management
Illinois
– – -35,859 Closed
GC
829
Grimes & Company
Massachusetts
– – -26,182 Closed
SW
830
SVB Wealth
Massachusetts
– – -23,373 Closed
PPWP
831
Proquility Private Wealth Partners
Nevada
– – -22,426 Closed
BSAM
832
Blue Square Asset Management
New York
– – -20,150 Closed
GWA
833
Genesis Wealth Advisors
Massachusetts
– – -15,383 Closed
Renaissance Technologies
834
Renaissance Technologies
New York
– – -13,100 Closed
BBVA
835
Banco Bilbao Vizcaya Argentaria
Spain
– – -12,200 Closed
PP
836
Prudential plc
United Kingdom
– – -10,750 Closed
BGA
837
Battery Global Advisors
Massachusetts
– – -9,233 Closed
DAM
838
Deltec Asset Management
New York
– – -7,500 Closed
PEAK6
839
PEAK6
Illinois
– – -7,437 Closed
CC
840
Centiva Capital
New York
– – -4,739 Closed
YIH
841
Y-Intercept (HK)
Hong Kong
– – -3,863 Closed
JFG
842
Jefferies Financial Group
New York
– – -3,806 Closed
SSA
843
Schonfeld Strategic Advisors
New York
– – -3,789 Closed
KW
844
KWB Wealth
California
– – -3,200 Closed
OAC
845
OMERS Administration Corp
Ontario, Canada
– – -3,100 Closed
PCH
846
PGIM Custom Harvest
New Jersey
– – -2,196 Closed
BKA
847
Brick & Kyle Associates
Pennsylvania
– – -2,143 Closed
NG
848
Northstar Group
New York
– – -2,118 Closed
CNC
849
Citizens & Northern Corp
Pennsylvania
– – -2,084 Closed
PG
850
Patten Group
Tennessee
– – -2,029 Closed
32 33
34
35 36