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iShares Biotechnology ETF
IBB

803 hedge funds and large institutions have $4.63B invested in iShares Biotechnology ETF in 2025 Q3 according to their latest regulatory filings, with 85 funds opening new positions, 156 increasing their positions, 326 reducing their positions, and 65 closing their positions.

New
Increased
Maintained
Reduced
Closed

31% more first-time investments, than exits

New positions opened: 85 | Existing positions closed: 65

17% more capital invested

Capital invested by funds: $3.94B → $4.63B (+$686M)

6.06% more ownership

Funds ownership: 74.02% → 80.08% (+6.1%)

1% more funds holding

Funds holding: 797 → 803 (+6)

0% more funds holding in top 10

Funds holding in top 10: 7 → 7 (0)

27% less call options, than puts

Call options by funds: $185M | Put options by funds: $253M

52% less repeat investments, than reductions

Existing positions increased: 156 | Existing positions reduced: 326

Holders
803
Holders Change
+6
Holders Change %
+0.75%
% of All Funds
10.54%
Holding in Top 10
7
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.09%
New
85
Increased
156
Reduced
326
Closed
65
Calls
$185M
Puts
$253M
Net Calls
-$68.5M
Net Calls Change
-$116M

Top Buyers

1
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
+$198M
2
JFG
Jefferies Financial Group
New York
+$61.5M
3
Jane Street
Jane Street
New York
+$38.2M
4
JP Morgan Chase
JP Morgan Chase
New York
+$31M
5
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
+$20.5M

Top Sellers

1
Morgan Stanley
Morgan Stanley
New York
-$67.4M
2
UBS Group
UBS Group
Switzerland
-$51.4M
3
Citigroup
Citigroup
New York
-$48.2M
4
Bank of America
Bank of America
North Carolina
-$33.2M
5
Citadel Advisors
Citadel Advisors
Florida
-$15.1M
Name Holding Trade Value Shares
Change 		Change in
Stake
RS
801
Rakuten Securities
Japan
$433 -$2.46K -18 -86%
GA
802
Guerra Advisors
Florida
$433 +$409 +3 New
MCM
803
Manchester Capital Management
Vermont
$145 – – –
BWM
804
Bernard Wealth Management
Michigan
$145 +$136 +1 New
Capital Fund Management (CFM)
805
Capital Fund Management (CFM)
France
– -$12.6M -92,567 Closed
GF
806
Gray Foundation
New York
– -$7.78M -61,512 Closed
Mirae Asset Global ETFs Holdings
807
Mirae Asset Global ETFs Holdings
Hong Kong
– -$4.11M -32,500 Closed
AC
808
Aristides Capital
Kentucky
– -$3.6M -28,467 Closed
Wellington Management Group
809
Wellington Management Group
Massachusetts
– -$2.7M -21,313 Closed
CI
810
CAZ Investments
Texas
– -$2.53M -20,000 Closed
Parallax Volatility Advisers
811
Parallax Volatility Advisers
California
– -$2.46M -19,416 Closed
HF
812
HRT Financial
New York
– -$1.28M -10,087 Closed
CV
813
Counterweight Ventures
North Carolina
– -$1.18M -9,315 Closed
PFGIA
814
Patriot Financial Group Insurance Agency
Massachusetts
– -$838K -6,626 Closed
MS
815
Maven Securities
Jersey
– -$761K -6,014 Closed
IC
816
Ikarian Capital
Texas
– -$728K -5,755 Closed
JGC
817
J. Goldman & Co
New York
– -$764K -5,600 Closed
MPCL
818
My Personal CFO LLC
Washington
– -$650K -5,140 Closed
MA
819
MYDA Advisors
New York
– -$633K -5,000 Closed
Walleye Capital
820
Walleye Capital
New York
– -$589K -4,655 Closed
TSS
821
Two Sigma Securities
New York
– -$588K -4,647 Closed
BBVA
822
Banco Bilbao Vizcaya Argentaria
Spain
– -$588K -4,645 Closed
Bank Julius Baer & Co
823
Bank Julius Baer & Co
Switzerland
– -$517K -4,083 Closed
MCA
824
Magnolia Capital Advisors
Mississippi
– -$471K -3,725 Closed
IWN
825
Independent Wealth Network
Iowa
– -$426K -3,363 Closed
31 32
33
34 35

IBB Hedge Fund Activity: Q3 2025 in Review

803 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in iShares Biotechnology ETF (IBB) for Q3 2025, worth a combined $4.63B — up 17% from $3.94B a quarter earlier.

Buyers outnumbered sellers: 85 funds opened new IBB positions and 65 closed out — a net gain of 20 holders — while 156 added to existing stakes and 326 trimmed.

The largest buyer was BNP Paribas Financial Markets, adding an estimated $198M. The largest seller was Morgan Stanley, cutting an estimated $67.4M.

  • 803 institutional investors held iShares Biotechnology ETF (IBB) as of Q3 2025, up from 797 in Q2 2025.
  • Funds reported $4.63B of iShares Biotechnology ETF stock for Q3 2025, up 17% quarter-over-quarter.
  • 85 funds opened new iShares Biotechnology ETF positions in Q3 2025 and 65 closed out, a net change of +20 holders.
  • The largest iShares Biotechnology ETF buyer in Q3 2025 was BNP Paribas Financial Markets, an estimated $198M added.
  • The largest iShares Biotechnology ETF seller in Q3 2025 was Morgan Stanley, an estimated $67.4M sold.

Based on aggregated 13F filings for Q3 2025.