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iShares Biotechnology ETF
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Overview Fund Activity

778 hedge funds and large institutions have $3.92B invested in iShares Biotechnology ETF in 2025 Q2 according to their latest regulatory filings, with 56 funds opening new positions, 135 increasing their positions, 340 reducing their positions, and 82 closing their positions.

Holders
778
Holders Change
-43
Holders Change %
-5.24%
% of All Funds
10.45%
Holding in Top 10
7
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-12.5%
% of All Funds
0.09%
New
56
Increased
135
Reduced
340
Closed
82
Calls
$140M
Puts
$129M
Net Calls
+$11.5M
Net Calls Change
+$349M

Top Buyers

1
Goldman Sachs
1
Goldman Sachs
New York
$314M
2
Citigroup
2
Citigroup
New York
$515M
3
Morgan Stanley
3
Morgan Stanley
New York
$458M
4
JPMorgan Chase & Co
4
JPMorgan Chase & Co
New York
$105M
5
ERSOT
5
Employees Retirement System of Texas
Texas
$25M

Top Sellers

1
Bank of America
1
Bank of America
North Carolina
$776M
2
MMEA
2
Main Management ETF Advisors
California
$0
3
BNP Paribas Financial Markets
3
BNP Paribas Financial Markets
France
$58.6M
4
Barclays
4
Barclays
United Kingdom
$49.4M
5
Two Sigma Investments
5
Two Sigma Investments
New York
$0
Name Market Value Shares Shares
Change 		Shares
Change %
WPWM
776
Western Pacific Wealth Management
Illinois
$382 3 – –
NRG
777
Nemes Rush Group
Michigan
$253 2 -6,379 -100%
MCM
778
Manchester Capital Management
Vermont
$127 1 – –
SSG
779
Summit Securities Group
New York
$127 1 +1 New
OLVIG
780
Oliver Lagore Vanvalin Investment Group
Michigan
– – – –
MMEA
781
Main Management ETF Advisors
California
– – -612,180 Closed
Two Sigma Investments
782
Two Sigma Investments
New York
– – -277,807 Closed
MFS
783
Madrona Financial Services
Washington
– – -81,150 Closed
GS
784
GTS Securities
New York
– – -72,376 Closed
MIG
785
McGuire Investment Group
Rhode Island
– – -59,752 Closed
D.E. Shaw & Co
786
D.E. Shaw & Co
New York
– – -54,801 Closed
SA
787
Sicart Associates
New York
– – -45,503 Closed
MCP
788
Mirador Capital Partners
California
– – -30,626 Closed
PFA
789
Pinnacle Family Advisors
Missouri
– – -23,806 Closed
HI
790
Hudock Inc
Pennsylvania
– – -20,538 Closed
Twin Tree Management
791
Twin Tree Management
Texas
– – -20,002 Closed
GS
792
GWN Securities
Florida
– – -18,146 Closed
AFA
793
Arlington Financial Advisors
California
– – -16,861 Closed
HAC
794
Harbor Advisory Corp
New Hampshire
– – -11,761 Closed
PWP
795
Pursue Wealth Partners
California
– – -11,137 Closed
SC
796
SummitTX Capital
Texas
– – -10,970 Closed
CWA
797
Clarus Wealth Advisors
Arizona
– – -10,831 Closed
TFCP
798
Twin Focus Capital Partners
Massachusetts
– – -10,697 Closed
FTUS
799
Flow Traders U.S.
New York
– – -9,207 Closed
BPC
800
Banque Pictet & Cie
Switzerland
– – -8,690 Closed
30 31
32
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