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iShares Biotechnology ETF

955 hedge funds and large institutions have $6.94B invested in iShares Biotechnology ETF in 2025 Q4 according to their latest regulatory filings, with 215 funds opening new positions, 275 increasing their positions, 219 reducing their positions, and 44 closing their positions.

New
Increased
Maintained
Reduced
Closed

389% more first-time investments, than exits

New positions opened: 215 | Existing positions closed: 44

71% more funds holding in top 10

Funds holding in top 10: 712 (+5)

50% more capital invested

Capital invested by funds: $4.63B → $6.94B (+$2.31B)

26% more repeat investments, than reductions

Existing positions increased: 275 | Existing positions reduced: 219

19% more funds holding

Funds holding: 803955 (+152)

2.91% more ownership

Funds ownership: 80.08%82.98% (+2.9%)

1% less call options, than puts

Call options by funds: $257M | Put options by funds: $260M

Holders
955
Holders Change
+152
Holders Change %
+18.93%
% of All Funds
11.62%
Holding in Top 10
12
Holding in Top 10 Change
+5
Holding in Top 10 Change %
+71.43%
% of All Funds
0.15%
New
215
Increased
275
Reduced
219
Closed
44
Calls
$257M
Puts
$260M
Net Calls
-$3.01M
Net Calls Change
+$65.5M
Name Holding Trade Value Shares
Change
Change in
Stake
CM
51
Caption Management
Oklahoma
$12.5M -$731K -4,500 -6%
AP
52
Appleton Partners
Massachusetts
$12.5M -$2.11K -13 -0%
BCM
53
Bronte Capital Management
Australia
$12.2M -$34M -209,072 -74%
GIA
54
Gladstone Institutional Advisory
Florida
$12M +$10.9M +67,012 +1,669%
FMI
55
Factory Mutual Insurance
Massachusetts
$12M
HighTower Advisors
56
HighTower Advisors
Illinois
$11.9M +$3M +18,479 +36%
Cambridge Investment Research Advisors
57
Cambridge Investment Research Advisors
Iowa
$11.6M +$1.8M +11,065 +19%
DCM
58
DAFNA Capital Management
California
$11.5M -$5.59M -34,405 -34%
Creative Planning
59
Creative Planning
Kansas
$11.4M +$39.8K +245 +0.4%
CA
60
Cumberland Advisors
Florida
$10.8M -$189K -1,165 -2%
HW
61
Hamilton Wealth
California
$10.7M +$4.88M +30,051 +89%
FNFDCM
62
Folger Nolan Fleming Douglas Capital Management
District of Columbia
$10.4M -$96.6K -595 -1%
AC
63
Apella Capital
Connecticut
$9.72M +$9.35M +57,594 New
TWM
64
Tradition Wealth Management
Minnesota
$9.72M +$28.9K +178 +0.3%
Manulife (Manufacturers Life Insurance)
65
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$9.71M +$9.35M +57,545 New
PGFC
66
Peapack-Gladstone Financial Corp
New Jersey
$9.44M -$203K -1,249 -2%
HWM
67
Horizon Wealth Management
Illinois
$9.22M +$8.88M +54,657 New
HI
68
Humankind Investments
New York
$9.2M +$8.12M +50,000 +1,111%
NAM
69
NTV Asset Management
West Virginia
$9.15M +$134K +825 +2%
AWM
70
Accurate Wealth Management
Florida
$9.14M +$29.7K +183 +0.3%
Brown Advisory
71
Brown Advisory
Maryland
$9.12M -$465K -2,865 -5%
VCM
72
Virtue Capital Management
Tennessee
$9.03M +$8.68M +53,414 New
BPA
73
Beacon Pointe Advisors
California
$8.73M +$1.71M +10,545 +26%
Cerity Partners
74
Cerity Partners
New York
$8.08M +$273K +1,681 +4%
Allspring Global Investments
75
Allspring Global Investments
North Carolina
$7.93M +$7.6M +46,806 +46,806%