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iShares Biotechnology ETF
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Overview Fund Activity

778 hedge funds and large institutions have $3.92B invested in iShares Biotechnology ETF in 2025 Q2 according to their latest regulatory filings, with 56 funds opening new positions, 135 increasing their positions, 340 reducing their positions, and 82 closing their positions.

Holders
778
Holders Change
-43
Holders Change %
-5.24%
% of All Funds
10.45%
Holding in Top 10
7
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-12.5%
% of All Funds
0.09%
New
56
Increased
135
Reduced
340
Closed
82
Calls
$140M
Puts
$129M
Net Calls
+$11.5M
Net Calls Change
+$349M

Top Buyers

1
Goldman Sachs
1
Goldman Sachs
New York
$314M
2
Citigroup
2
Citigroup
New York
$515M
3
Morgan Stanley
3
Morgan Stanley
New York
$458M
4
JPMorgan Chase & Co
4
JPMorgan Chase & Co
New York
$105M
5
ERSOT
5
Employees Retirement System of Texas
Texas
$25M

Top Sellers

1
Bank of America
1
Bank of America
North Carolina
$776M
2
MMEA
2
Main Management ETF Advisors
California
$0
3
BNP Paribas Financial Markets
3
BNP Paribas Financial Markets
France
$58.6M
4
Barclays
4
Barclays
United Kingdom
$49.4M
5
Two Sigma Investments
5
Two Sigma Investments
New York
$0
Name Market Value Shares Shares
Change 		Shares
Change %
Focus Partners Wealth
26
Focus Partners Wealth
Massachusetts
$13.6M 107,440 -6,610 -6%
Thrivent Financial for Lutherans
27
Thrivent Financial for Lutherans
Minnesota
$13.4M 105,706 +7,750 +8%
Ameriprise
28
Ameriprise
Minnesota
$13.2M 104,144 -13,991 -12%
DCM
29
DAFNA Capital Management
California
$13M 102,500 – –
Canada Life
30
Canada Life
Manitoba, Canada
$12.8M 100,936 -1,717 -2%
IHL
31
Investment House LLC
California
$12M 94,948 +9,292 +11%
Capital Fund Management (CFM)
32
Capital Fund Management (CFM)
France
$11.7M 92,567 -48,619 -34%
Osaic Holdings
33
Osaic Holdings
Arizona
$11.4M 86,628 -4,708 -5%
MIM
34
Miller Investment Management
Pennsylvania
$10.4M 81,949 -115 -0.1%
DWP
35
Destiny Wealth Partners
Florida
$9.59M 75,784 +5,919 +8%
AP
36
Appleton Partners
Massachusetts
$9.35M 73,894 -4,488 -6%
FMI
37
Factory Mutual Insurance
Massachusetts
$8.98M 71,000 – –
MCM
38
MAI Capital Management
Ohio
$8.9M 70,346 -27,812 -28%
MML Investors Services
39
MML Investors Services
Massachusetts
$8.52M 67,355 +2,302 +4%
CA
40
Cumberland Advisors
Florida
$8.34M 65,918 -7,525 -10%
Creative Planning
41
Creative Planning
Kansas
$8.28M 65,446 -2,180 -3%
Squarepoint
42
Squarepoint
New York
$8.28M 65,442 -6,554 -9%
EAM
43
Erste Asset Management
Austria
$8.11M 64,100 +1,100 +2%
ATPW
44
Ashton Thomas Private Wealth
Arizona
$8.06M 63,691 +56,369 +770%
FNFDCM
45
Folger Nolan Fleming Douglas Capital Management
District of Columbia
$7.92M 62,617 -1,495 -2%
GF
46
Gray Foundation
New York
$7.78M 61,512 -103,360 -63%
Cetera Investment Advisers
47
Cetera Investment Advisers
Illinois
$7.77M 61,454 -1,467 -2%
Brown Advisory
48
Brown Advisory
Maryland
$7.58M 59,920 -20,590 -26%
PGFC
49
Peapack-Gladstone Financial Corp
New Jersey
$7.39M 58,429 -3,886 -6%
TWM
50
Tradition Wealth Management
Minnesota
$7.35M 58,062 +245 +0.4%
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