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iShares Biotechnology ETF
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Overview Fund Activity

821 hedge funds and large institutions have $3.97B invested in iShares Biotechnology ETF in 2025 Q1 according to their latest regulatory filings, with 49 funds opening new positions, 193 increasing their positions, 355 reducing their positions, and 78 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
821
Holders Change
-44
Holders Change %
-5.09%
% of All Funds
11.15%
Holding in Top 10
8
Holding in Top 10 Change
-3
Holding in Top 10 Change %
-27.27%
% of All Funds
0.11%
New
49
Increased
193
Reduced
355
Closed
78
Calls
$293M
Puts
$630M
Net Calls
-$338M
Net Calls Change
+$66.5M

Top Buyers

1
Citigroup
Citigroup
New York
$410M
2
UBS Group
UBS Group
Switzerland
$181M
3
Wells Fargo
Wells Fargo
California
$113M
4
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
$61.2M
5
Squarepoint
Squarepoint
New York
$9.21M

Top Sellers

1
Jane Street
Jane Street
New York
$32.8M
2
Morgan Stanley
Morgan Stanley
New York
$359M
3
Bank of America
Bank of America
North Carolina
$891M
4
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
$117M
5
Royal Bank of Canada
Royal Bank of Canada
Ontario, Canada
$97.8M
Name Holding Trade Value Shares
Change 		Shares
Change %
MC
376
Middleton & Co
Massachusetts
$460K – – –
GWS
377
Glassman Wealth Services
Virginia
$460K – – –
MAM
378
Marotta Asset Management
Virginia
$458K – – –
LWM
379
Liberty Wealth Management
California
$457K +$256 +2 +0.1%
CWC
380
Carolinas Wealth Consulting
North Carolina
$456K +$19.3K +151 +4%
AQR Capital Management
381
AQR Capital Management
Connecticut
$455K +$455K +3,557 New
CCG
382
Coastwise Capital Group
California
$454K +$256 +2 +0.1%
PCP
383
Proficio Capital Partners
Massachusetts
$453K – – –
CHAM
384
Clear Harbor Asset Management
Connecticut
$451K +$48.6K +380 +12%
TBC
385
Ted Buchan & Co
California
$450K +$111K +870 +33%
EWM
386
Endowment Wealth Management
Wisconsin
$450K +$162K +1,263 +56%
HWAM
387
Hennion & Walsh Asset Management
New Jersey
$449K – – –
EIP
388
Ellis Investment Partners
Pennsylvania
$448K -$21.4K -167 -5%
National Bank of Canada
389
National Bank of Canada
Quebec, Canada
$444K -$47.1K -369 -10%
AFM
390
Abbot Financial Management
Massachusetts
$443K -$29.2K -228 -6%
IWN
391
Independent Wealth Network
Iowa
$442K -$9.72K -76 -2%
CWMGO
392
Capstone Wealth Management Group (Oregon)
Oregon
$435K -$24.7K -193 -5%
FPW
393
Flagship Private Wealth
Massachusetts
$433K +$384 +3 +0.1%
VNA
394
Valley National Advisers
Pennsylvania
$433K -$101K -793 -19%
IFWM
395
Institute for Wealth Management
Colorado
$432K – – –
BOPW
396
Brandywine Oak Private Wealth
Pennsylvania
$429K -$9.59K -75 -2%
TIAA Trust, National Association
397
TIAA Trust, National Association
North Carolina
$426K +$22.9K +179 +6%
CG
398
Caprock Group
Idaho
$423K -$4.61K -36 -1%
COFSG
399
Carbahal Olsen Financial Services Group
California
$422K -$2.3K -18 -0.5%
CIBC World Market
400
CIBC World Market
Ontario, Canada
$422K -$96.8K -757 -19%
14 15
16
17 18