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iShares Biotechnology ETF
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Overview Fund Activity

782 hedge funds and large institutions have $3.93B invested in iShares Biotechnology ETF in 2025 Q2 according to their latest regulatory filings, with 57 funds opening new positions, 136 increasing their positions, 342 reducing their positions, and 82 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
782
Holders Change
-39
Holders Change %
-4.75%
% of All Funds
10.49%
Holding in Top 10
7
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-12.5%
% of All Funds
0.09%
New
57
Increased
136
Reduced
342
Closed
82
Calls
$216M
Puts
$168M
Net Calls
+$47.6M
Net Calls Change
+$385M

Top Buyers

1
Goldman Sachs
Goldman Sachs
New York
$314M
2
Citigroup
Citigroup
New York
$515M
3
Morgan Stanley
Morgan Stanley
New York
$458M
4
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
$105M
5
ERSOT
Employees Retirement System of Texas
Texas
$25M

Top Sellers

1
Bank of America
Bank of America
North Carolina
$776M
2
MMEA
Main Management ETF Advisors
California
$0
3
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
$58.6M
4
Barclays
Barclays
United Kingdom
$49.4M
5
Two Sigma Investments
Two Sigma Investments
New York
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
EWA
276
Evolution Wealth Advisors
Florida
$711K -$16.6K -131 -2%
WT
277
Whittier Trust
California
$710K -$56.2K -444 -7%
JGC
278
J. Goldman & Co
New York
$708K +$708K +5,600 New
CFB
279
Cullen/Frost Bankers
Texas
$705K – – –
B
280
Bailard
California
$704K +$253 +2 +0%
AWS
281
Atria Wealth Solutions
New York
$703K -$989K -7,742 -58%
TSWM
282
Tyler-Stone Wealth Management
Ohio
$698K – – –
CCWM
283
Cassaday & Co Wealth Management
Virginia
$697K – – –
Vontobel Holding
284
Vontobel Holding
Switzerland
$691K +$43.1K +341 +7%
XT
285
XTX Topco
Cayman Islands
$687K +$108K +855 +19%
CA
286
Calton & Associates
Florida
$686K -$10.4K -82 -1%
MLL
287
Moody Lynn & Lieberson
Massachusetts
$684K – – –
FMC
288
First Merchants Corp
Indiana
$681K – – –
DP
289
Dearborn Partners
Illinois
$681K -$11.1K -88 -2%
CBA
290
Coastal Bridge Advisors
Connecticut
$680K +$680K +5,377 New
AQR Capital Management
291
AQR Capital Management
Connecticut
$678K +$228K +1,806 +51%
NFC
292
Northeast Financial Consultants
Connecticut
$676K -$185K -1,464 -21%
SI
293
Stephens Inc
Arkansas
$672K +$59.6K +471 +10%
FFA
294
Farther Finance Advisors
California
$671K -$108K -852 -14%
FCP
295
Fidelis Capital Partners
Florida
$664K +$5.65K +43 +0.9%
UCFA
296
United Capital Financial Advisors
Texas
$660K -$431K -3,405 -40%
Kayne Anderson Rudnick Investment Management
297
Kayne Anderson Rudnick Investment Management
California
$659K – – –
MPCL
298
My Personal CFO LLC
Washington
$650K – – –
PWP
299
Principle Wealth Partners
Connecticut
$643K -$9.99K -79 -2%
ATC
300
Advantage Trust Company
Kansas
$639K -$10.9K -86 -2%
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