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iShares Biotechnology ETF
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Overview Fund Activity

782 hedge funds and large institutions have $3.93B invested in iShares Biotechnology ETF in 2025 Q2 according to their latest regulatory filings, with 57 funds opening new positions, 136 increasing their positions, 342 reducing their positions, and 82 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
782
Holders Change
-39
Holders Change %
-4.75%
% of All Funds
10.49%
Holding in Top 10
7
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-12.5%
% of All Funds
0.09%
New
57
Increased
136
Reduced
342
Closed
82
Calls
$216M
Puts
$168M
Net Calls
+$47.6M
Net Calls Change
+$385M

Top Buyers

1
Goldman Sachs
Goldman Sachs
New York
$314M
2
Citigroup
Citigroup
New York
$515M
3
Morgan Stanley
Morgan Stanley
New York
$458M
4
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
$105M
5
ERSOT
Employees Retirement System of Texas
Texas
$25M

Top Sellers

1
Bank of America
Bank of America
North Carolina
$776M
2
MMEA
Main Management ETF Advisors
California
$0
3
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
$58.6M
4
Barclays
Barclays
United Kingdom
$49.4M
5
Two Sigma Investments
Two Sigma Investments
New York
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
LA
251
LM Advisors
California
$831K -$26.6K -210 -3%
Carson Wealth (CWM LLC)
252
Carson Wealth (CWM LLC)
Nebraska
$825K -$173K -1,371 -17%
WGS
253
Washington Growth Strategies
District of Columbia
$825K +$809K +6,396 +4,997%
ORC
254
O'Rourke & Company
Massachusetts
$823K -$27.3K -216 -3%
NM
255
NWI Management
New York
$822K – – –
AAS
256
Avantax Advisory Services
Texas
$818K +$16.2K +128 +2%
WB
257
Webster Bank
Connecticut
$811K – – –
SVWAG
258
Sound View Wealth Advisors Group
Georgia
$809K -$10.1K -80 -1%
SWP
259
Stratos Wealth Partners
Ohio
$809K -$68.8K -544 -8%
MWM
260
Modera Wealth Management
New Jersey
$791K +$31.5K +249 +4%
Walleye Trading
261
Walleye Trading
New York
$769K +$769K +6,082 New
AF
262
Allworth Financial
California
$767K +$546K +4,313 +247%
MS
263
Maven Securities
Jersey
$761K +$761K +6,014 New
SW
264
SteelPeak Wealth
California
$756K -$16.3K -129 -2%
OIA
265
OneDigital Investment Advisors
Kansas
$741K -$144K -1,142 -16%
SCA
266
Snowden Capital Advisors
New York
$736K -$3.42K -27 -0.5%
SW
267
SlateStone Wealth
Florida
$732K -$15.2K -120 -2%
LWM
268
Lyell Wealth Management
California
$730K -$1.33M -10,508 -65%
IC
269
IEQ Capital
California
$730K -$38.2K -302 -5%
STA
270
Summit Trail Advisors
New York
$729K +$729K +5,760 New
IC
271
Ikarian Capital
Texas
$728K +$728K +5,755 New
RWP
272
RWA Wealth Partners
Massachusetts
$725K -$351K -2,773 -33%
CIA
273
Cladis Investment Advisory
Montana
$722K – – –
HCA
274
Harbour Capital Advisors
Virginia
$721K – – –
BBHC
275
Brown Brothers Harriman & Co
New York
$713K -$3.04K -24 -0.4%
9 10
11
12 13