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Gyre Therapeutics
GYRE

46 hedge funds and large institutions have $20.1M invested in Gyre Therapeutics in 2025 Q1 according to their latest regulatory filings, with 9 funds opening new positions, 15 increasing their positions, 14 reducing their positions, and 4 closing their positions.

New
Increased
Maintained
Reduced
Closed

125% more first-time investments, than exits

New positions opened: 9 | Existing positions closed: 4

12% more funds holding

Funds holding: 41 → 46 (+5)

7% more repeat investments, than reductions

Existing positions increased: 15 | Existing positions reduced: 14

0.96% more ownership

Funds ownership: 2.08% → 3.04% (+0.96%)

7% less capital invested

Capital invested by funds: $21.6M → $20.1M (-$1.48M)

Holders
46
Holders Change
+5
Holders Change %
+12.2%
% of All Funds
0.62%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
9
Increased
15
Reduced
14
Closed
4
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

Rank Fund Capital Flow
1
Vanguard Group
Vanguard Group
Pennsylvania
+$8.49M
2
American Century Companies
American Century Companies
Missouri
+$261K
3
SS
SBI Securities
Japan
+$246K
4
Susquehanna International Group
Susquehanna International Group
Pennsylvania
+$186K
5
BlackRock
BlackRock
New York
+$170K

Top Sellers

Rank Fund Capital Flow
1
UBS Group
UBS Group
Switzerland
-$359K
2
Goldman Sachs
Goldman Sachs
New York
-$112K
3
Charles Schwab
Charles Schwab
California
-$34.5K
4
Belvedere Trading
Belvedere Trading
Illinois
-$29.8K
5
Barclays
Barclays
United Kingdom
-$22.9K
Name Holding Trade Value Shares
Change 		Change in
Stake
Lazard Asset Management
26
Lazard Asset Management
New York
$6K +$9.14K +833 New
AIP
27
Ameritas Investment Partners
Nebraska
$5.27K – – –
Legal & General Group
28
Legal & General Group
United Kingdom
$4.64K – – –
AWM
29
Activest Wealth Management
Florida
$4.12K – – –
California State Teachers Retirement System (CalSTRS)
30
California State Teachers Retirement System (CalSTRS)
California
$3.9K – – –
BNP Paribas Financial Markets
31
BNP Paribas Financial Markets
France
$3.82K -$9.86K -899 -64%
Group One Trading
32
Group One Trading
Illinois
$3.74K +$5.32K +485 New
Royal Bank of Canada
33
Royal Bank of Canada
Ontario, Canada
$3K -$4.58K -418 -52%
Fidelity Investments
34
Fidelity Investments
Massachusetts
$2.9K -$9.65K -880 -70%
AB
35
Amalgamated Bank
New York
$2K – – –
GI
36
GAMMA Investing
California
$1.82K +$2.46K +224 +1,867%
Carson Wealth (CWM LLC)
37
Carson Wealth (CWM LLC)
Nebraska
$1K +$1.34K +122 +813%
SCM
38
Sterling Capital Management
North Carolina
$818 -$1.21K -110 -51%
ACM
39
Aster Capital Management
United Arab Emirates
$684 +$647 +59 New
Nisa Investment Advisors
40
Nisa Investment Advisors
Missouri
$471 -$252 -23 -27%
EWA
41
EverSource Wealth Advisors
Alabama
$170 +$241 +22 New
US Bancorp
42
US Bancorp
Minnesota
$131 +$186 +17 New
Osaic Holdings
43
Osaic Holdings
Arizona
$85 -$329 -30 -73%
TWD
44
True Wealth Design
Ohio
$47 +$66 +6 New
IA
45
IFP Advisors
Florida
$15 – – –
Belvedere Trading
46
Belvedere Trading
Illinois
– -$29.8K -2,461 Closed
PMAM
47
Picton Mahoney Asset Management
Ontario, Canada
– -$14K -1,120 Closed
FDCDDQ
48
Federation des caisses Desjardins du Quebec
Quebec, Canada
– -$908 -75 Closed
PA
49
Parallel Advisors
California
– -$182 -15 Closed
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GYRE Hedge Fund Activity: Q1 2025 in Review

46 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in Gyre Therapeutics (GYRE) for Q1 2025, worth a combined $20.1M — down 6.9% from $21.6M a quarter earlier.

Buyers outnumbered sellers: 9 funds opened new GYRE positions and 4 closed out — a net gain of 5 holders — while 15 added to existing stakes and 14 trimmed.

The largest buyer was Vanguard Group, adding an estimated $8.49M. The largest seller was UBS Group, cutting an estimated $359K.

  • 46 institutional investors held Gyre Therapeutics (GYRE) as of Q1 2025, up from 41 in Q4 2024.
  • Funds reported $20.1M of Gyre Therapeutics stock for Q1 2025, down 6.9% quarter-over-quarter.
  • 9 funds opened new Gyre Therapeutics positions in Q1 2025 and 4 closed out, a net change of +5 holders.
  • The largest Gyre Therapeutics buyer in Q1 2025 was Vanguard Group, an estimated $8.49M added.
  • The largest Gyre Therapeutics seller in Q1 2025 was UBS Group, an estimated $359K sold.

Based on aggregated 13F filings for Q1 2025.