|
1
|
Baker Bros. Advisors
New York
|
$989M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$425M
|
+$55.3M
|
+701,050
|
+18%
|
|
|
3
|
Capital Research Global Investors
Los Angeles,
California
|
$378M
|
+$512K
|
+6,486
|
+0.2%
|
|
|
4
|
Columbia Wanger Asset Management
Chicago,
Illinois
|
$357M
|
-$6.31M
|
-79,912
|
-2%
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$123M
|
+$2.12M
|
+26,900
|
+2%
|
|
|
6
|
BB Biotech
Schaffhausen,
Switzerland
|
$105M
|
+$2.92M
|
+37,000
|
+3%
|
|
|
7
|
Capital World Investors
Los Angeles,
California
|
$95.8M
|
+$7.02M
|
+89,000
|
+9%
|
|
|
8
|
BlackRock Fund Advisors
San Francisco,
California
|
$87.2M
|
+$5.57M
|
+70,643
|
+8%
|
|
|
9
|
Janus Henderson Investors US
Denver,
Colorado
|
$79.1M
|
+$2.32M
|
+29,364
|
+4%
|
|
|
10
|
BlackRock Institutional Trust
San Francisco,
California
|
$53.9M
|
-$965K
|
-12,228
|
-2%
|
|
|
11
|
AllianceBernstein
Nashville,
Tennessee
|
$51.1M
|
-$2.65M
|
-33,597
|
-6%
|
|
|
12
|
State Street
Boston,
Massachusetts
|
$49.2M
|
-$3.11M
|
-39,392
|
-7%
|
|
|
13
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$45.5M
|
+$38.2M
|
+484,100
|
+7,335%
|
|
|
14
|
|
$43.2M
|
+$156K
|
+1,976
|
+0.4%
|
|
|
15
|
Wells Fargo
San Francisco,
California
|
$40.3M
|
-$11.3M
|
-143,718
|
-25%
|
|
|
16
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$40.2M
|
-$1.85M
|
-23,505
|
-5%
|
|
|
17
|
Sectoral Asset Management
Montreal,
Quebec, Canada
|
$33.8M
|
-$18.8M
|
-238,461
|
-40%
|
|
|
18
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$22.2M
|
+$1.46M
|
+18,491
|
+8%
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
$21.6M
|
-$662K
|
-8,392
|
-3%
|
|
|
20
|
|
$21.3M
|
+$8.91M
|
+112,909
|
+97%
|
|
|
21
|
Tekla Capital Management
Boston,
Massachusetts
|
$20.7M
|
–
|
–
|
–
|
|
|
22
|
Allianz Asset Management
Munich,
Germany
|
$19.6M
|
+$6.36M
|
+80,540
|
+61%
|
|
|
23
|
|
$19M
|
+$1.16M
|
+14,676
|
+8%
|
|
|
24
|
|
$14M
|
+$558K
|
+7,067
|
+5%
|
|
|
25
|
Ameriprise
Minneapolis,
Minnesota
|
$13.2M
|
+$14.2K
|
+180
|
+0.1%
|
|
