|
1
|
Redmile Group
San Francisco,
California
|
$505M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$279M
|
+$22.2M
|
+634,545
|
+10%
|
|
|
3
|
|
$262M
|
+$16.3M
|
+466,488
|
+8%
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$251M
|
+$41.1M
|
+1,177,511
|
+23%
|
|
|
5
|
Johnson & Johnson Innovation - JJDC
New Brunswick,
New Jersey
|
$135M
|
–
|
–
|
–
|
|
|
6
|
Janus Henderson Group
London,
|
$127M
|
-$17.2M
|
-492,685
|
-13%
|
|
|
7
|
Farallon Capital Management
San Francisco,
California
|
$125M
|
-$13.1M
|
-375,000
|
-11%
|
|
|
8
|
|
$122M
|
–
|
–
|
–
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$116M
|
-$6.97M
|
-199,533
|
-6%
|
|
|
10
|
Citadel Advisors
Miami,
Florida
|
$104M
|
-$23.9M
|
-685,907
|
-21%
|
|
|
11
|
Victory Capital Management
San Antonio,
Texas
|
$97.3M
|
-$4.5M
|
-128,848
|
-5%
|
|
|
12
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$93.4M
|
+$37.5M
|
+1,075,400
|
+85%
|
|
|
13
|
Grosvenor Holdings
Chicago,
Illinois
|
$93.4M
|
–
|
–
|
–
|
|
|
14
|
Bellevue Group
Kuesnacht,
Switzerland
|
$88.6M
|
+$8.94M
|
+256,100
|
+13%
|
|
|
15
|
|
$60M
|
-$10.5M
|
-300,000
|
-17%
|
|
|
16
|
ARK Investment Management
St. Petersburg,
Florida
|
$57.6M
|
+$14.7M
|
+420,140
|
+41%
|
|
|
17
|
Pictet Asset Management (UK)
London,
United Kingdom
|
$52.7M
|
+$706K
|
+20,221
|
+2%
|
|
|
18
|
|
$52.3M
|
+$9.28M
|
+265,771
|
+25%
|
|
|
19
|
Franklin Resources
San Mateo,
California
|
$44.7M
|
-$1.14M
|
-32,722
|
-3%
|
|
|
20
|
Geode Capital Management
Boston,
Massachusetts
|
$44.1M
|
+$2.52M
|
+72,164
|
+7%
|
|
|
21
|
Jennison Associates
New York
|
$40.6M
|
+$127K
|
+3,644
|
+0.4%
|
|
|
22
|
Northern Trust
Chicago,
Illinois
|
$36.7M
|
+$1.36M
|
+38,911
|
+4%
|
|
|
23
|
|
$34.9M
|
+$27.6M
|
+790,014
|
+942%
|
|
|
24
|
Polaris Venture Management Co V
Boston,
Massachusetts
|
$34.2M
|
-$9.95M
|
-284,947
|
-25%
|
|
|
25
|
Credit Suisse
Zurich,
Switzerland
|
$29.8M
|
-$1.99M
|
-56,989
|
-7%
|
|
