|
1
|
Franklin Resources
San Mateo,
California
|
$27.6M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$20M
|
–
|
–
|
–
|
|
|
3
|
EcoR1 Capital
San Francisco,
California
|
$11.5M
|
+$9.28M
|
+2,537,026
|
New
|
|
|
4
|
Polaris Venture Management Co V
Boston,
Massachusetts
|
$11.3M
|
–
|
–
|
–
|
|
|
5
|
BVF Inc
San Francisco,
California
|
$8.85M
|
-$6.64M
|
-1,814,153
|
-48%
|
|
|
6
|
Kingdon Capital Management
New York
|
$7.79M
|
-$3.31M
|
-903,889
|
-35%
|
|
|
7
|
Redmile Group
San Francisco,
California
|
$6.46M
|
–
|
–
|
–
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$5.26M
|
+$1.92M
|
+523,684
|
+83%
|
|
|
9
|
|
$2.78M
|
+$200K
|
+54,615
|
+10%
|
|
|
10
|
683 Capital Management
New York
|
$2.14M
|
+$1.72M
|
+470,000
|
New
|
|
|
11
|
Renaissance Technologies
New York
|
$1.34M
|
+$314K
|
+85,800
|
+41%
|
|
|
12
|
Wells Fargo
San Francisco,
California
|
$1.28M
|
+$928K
|
+253,732
|
+927%
|
|
|
13
|
Bridgeway Capital Management
Houston,
Texas
|
$1.14M
|
–
|
–
|
–
|
|
|
14
|
Millennium Management
New York
|
$891K
|
+$717K
|
+195,928
|
New
|
|
|
15
|
Telemetry Investments
New York
|
$682K
|
+$96.9K
|
+26,500
|
+21%
|
|
|
16
|
|
$655K
|
+$436K
|
+119,200
|
+480%
|
|
|
17
|
Geode Capital Management
Boston,
Massachusetts
|
$543K
|
+$15K
|
+4,098
|
+4%
|
|
|
18
|
|
$392K
|
+$316K
|
+86,289
|
New
|
|
|
19
|
Neuberger Berman Group
New York
|
$312K
|
+$251K
|
+68,600
|
New
|
|
|
20
|
Jacobs Levy Equity Management
Florham Park,
New Jersey
|
$276K
|
-$122K
|
-33,278
|
-35%
|
|
|
21
|
Bank of New York Mellon
New York
|
$271K
|
+$3.48K
|
+952
|
+2%
|
|
|
22
|
TFS Capital
West Chester,
Pennsylvania
|
$248K
|
+$200K
|
+54,598
|
New
|
|
|
23
|
Connor, Clark & Lunn Investment Management (CC&L)
Vancouver,
British Columbia, Canada
|
$188K
|
+$151K
|
+41,300
|
New
|
|
|
24
|
Segantii Capital Management
Hong Kong
|
$182K
|
+$146K
|
+39,999
|
New
|
|
|
25
|
Hillsdale Investment Management
Toronto,
Ontario, Canada
|
$160K
|
+$129K
|
+35,200
|
New
|
|
