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89bio
ETNB

Overview Fund Activity

183 hedge funds and large institutions have $1.58B invested in 89bio in 2025 Q2 according to their latest regulatory filings, with 30 funds opening new positions, 80 increasing their positions, 56 reducing their positions, and 33 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
183
Holders Change
-3
Holders Change %
-1.61%
% of All Funds
2.45%
Holding in Top 10
4
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+33.33%
% of All Funds
0.05%
New
30
Increased
80
Reduced
56
Closed
33
Calls
$3.66M
Puts
$17.4M
Net Calls
-$13.7M
Net Calls Change
-$9.12M

Top Buyers

1
Holocene Advisors
Holocene Advisors
New York
$30.1M
2
Point72 Asset Management
Point72 Asset Management
Connecticut
$22.3M
3
Adage Capital Partners
Adage Capital Partners
Massachusetts
$19.3M
4
Assenagon Asset Management
Assenagon Asset Management
Luxembourg
$21.3M
5
Morgan Stanley
Morgan Stanley
New York
$21.5M

Top Sellers

1
LGM
Logos Global Management
California
$0
2
BBL
Beck Bode LLC
Massachusetts
$0
3
Citadel Advisors
Citadel Advisors
Florida
$37.7M
4
RSCM
Rock Springs Capital Management
Maryland
$393K
5
Lord, Abbett & Co
Lord, Abbett & Co
New Jersey
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
Janus Henderson Group
1
Janus Henderson Group
United Kingdom
$204M +$3.2M +325,458 +2%
RCM
2
RA Capital Management
Massachusetts
$195M – – –
SCM
3
Suvretta Capital Management
New York
$140M -$1.23M -125,244 -0.9%
BlackRock
4
BlackRock
New York
$104M +$4.85M +494,080 +5%
DTC
5
Deep Track Capital
Connecticut
$93.3M +$1.8M +183,667 +2%
Vanguard Group
6
Vanguard Group
Pennsylvania
$80.9M +$10.6M +1,078,545 +15%
ACA
7
Avoro Capital Advisors
New York
$66.3M +$3.93M +400,000 +6%
State Street
8
State Street
Massachusetts
$41.7M +$2.16M +219,650 +5%
Pictet Asset Management
9
Pictet Asset Management
Switzerland
$39.6M -$1.66M -169,497 -4%
Citadel Advisors
10
Citadel Advisors
Florida
$37.7M -$12.3M -1,249,944 -25%
Westfield Capital Management
11
Westfield Capital Management
Massachusetts
$33.1M -$5.14M -523,924 -13%
Geode Capital Management
12
Geode Capital Management
Massachusetts
$30.6M +$2.1M +213,325 +7%
Holocene Advisors
13
Holocene Advisors
New York
$30.1M +$30.1M +3,065,387 New
PCH
14
Polar Capital Holdings
United Kingdom
$24.3M -$246K -25,000 -1%
Point72 Asset Management
15
Point72 Asset Management
Connecticut
$22.3M +$22.3M +2,274,151 New
Morgan Stanley
16
Morgan Stanley
New York
$21.5M +$15.3M +1,555,776 +247%
Assenagon Asset Management
17
Assenagon Asset Management
Luxembourg
$21.3M +$17.1M +1,742,299 +406%
SCM
18
Silverarc Capital Management
Massachusetts
$20M +$5.17M +526,589 +35%
Adage Capital Partners
19
Adage Capital Partners
Massachusetts
$19.3M +$19.3M +1,969,000 New
RI
20
RTW Investments
New York
$19.3M – – –
EA
21
Emerald Advisers
Pennsylvania
$18.1M +$2.88M +293,699 +19%
RG
22
Redmile Group
California
$15.2M -$3.35M -341,236 -18%
Goldman Sachs
23
Goldman Sachs
New York
$12.3M +$2.53M +257,636 +26%
Bank of America
24
Bank of America
North Carolina
$12.3M +$4.6M +468,002 +60%
WP
25
Woodline Partners
California
$12M +$5.13M +521,907 +74%
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