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89bio
ETNB

Overview Fund Activity

186 hedge funds and large institutions have $1.14B invested in 89bio in 2025 Q1 according to their latest regulatory filings, with 54 funds opening new positions, 90 increasing their positions, 33 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
186
Holders Change
+31
Holders Change %
+20%
% of All Funds
2.53%
Holding in Top 10
3
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+50%
% of All Funds
0.04%
New
54
Increased
90
Reduced
33
Closed
22
Calls
$3.12M
Puts
$7.7M
Net Calls
-$4.59M
Net Calls Change
+$2.92M

Top Buyers

1
RCM
RA Capital Management
Massachusetts
+$41.5M
2
Janus Henderson Group
Janus Henderson Group
United Kingdom
+$31.9M
3
SCM
Suvretta Capital Management
New York
+$30M
4
DTC
Deep Track Capital
Connecticut
+$20.6M
5
LGM
Logos Global Management
California
+$18.2M

Top Sellers

1
RI
RTW Investments
New York
-$40.1M
2
BI
BVF Inc
California
-$33.9M
3
FLSM
Frazier Life Sciences Management
California
-$7.82M
4
AllianceBernstein
AllianceBernstein
Tennessee
-$6.46M
5
Balyasny Asset Management
Balyasny Asset Management
Illinois
-$4.96M
Name Holding Trade Value Shares
Change 		Shares
Change %
Janus Henderson Group
1
Janus Henderson Group
United Kingdom
$165M +$31.9M +3,948,849 +24%
RCM
2
RA Capital Management
Massachusetts
$145M +$41.5M +5,714,285 +40%
SCM
3
Suvretta Capital Management
New York
$104M +$30M +4,132,548 +41%
BlackRock
4
BlackRock
New York
$73.2M +$15.9M +2,185,245 +28%
DTC
5
Deep Track Capital
Connecticut
$67.7M +$20.6M +2,838,084 +44%
Vanguard Group
6
Vanguard Group
Pennsylvania
$52.1M +$10.7M +1,471,278 +26%
ACA
7
Avoro Capital Advisors
New York
$46.2M +$16.4M +2,250,000 +55%
Citadel Advisors
8
Citadel Advisors
Florida
$37M +$2.6M +356,984 +8%
Pictet Asset Management
9
Pictet Asset Management
Switzerland
$30.6M +$8.71M +1,197,853 +40%
State Street
10
State Street
Massachusetts
$29.3M +$7.89M +1,085,075 +37%
Westfield Capital Management
11
Westfield Capital Management
Massachusetts
$28.3M +$57.8K +7,947 +0.2%
Geode Capital Management
12
Geode Capital Management
Massachusetts
$21.1M +$5.02M +690,366 +31%
LGM
13
Logos Global Management
California
$18.2M +$18.2M +2,500,000 New
PCH
14
Polar Capital Holdings
United Kingdom
$18.2M +$18.2M +2,500,000 New
RI
15
RTW Investments
New York
$14.3M -$40.1M -5,510,534 -74%
RG
16
Redmile Group
California
$13.7M -$2.04M -280,732 -13%
BBL
17
Beck Bode LLC
Massachusetts
$13.2M +$13.2M +1,815,524 New
EA
18
Emerald Advisers
Pennsylvania
$11.3M +$11.3M +1,550,671 New
SCM
19
Silverarc Capital Management
Massachusetts
$11M +$10.3M +1,413,987 +1,465%
UOWF
20
University of Wisconsin Foundation
Wisconsin
$8.38M +$1.72M +236,000 +26%
Northern Trust
21
Northern Trust
Illinois
$7.89M +$1.68M +230,677 +27%
EMFAT
22
Emerald Mutual Fund Advisers Trust
Pennsylvania
$7.87M +$7.87M +1,082,973 New
IHAM
23
Integral Health Asset Management
New York
$7.63M +$364K +50,000 +5%
NL
24
Nuveen LLC
North Carolina
$7.53M +$7.53M +1,035,957 New
Goldman Sachs
25
Goldman Sachs
New York
$7.24M +$1.37M +188,367 +23%
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