182 hedge funds and large institutions have $1.58B invested in 89bio in 2025 Q2 according to their latest regulatory filings, with 30 funds opening new positions, 79 increasing their positions, 56 reducing their positions, and 32 closing their positions.

Holders
182
Holders Change
-4
Holders Change %
-2.15%
% of All Funds
2.44%
Holding in Top 10
4
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+33.33%
% of All Funds
0.05%
New
30
Increased
79
Reduced
56
Closed
32
Calls
$3.66M
Puts
$11.3M
Net Calls
-$7.62M
Net Calls Change
-$3.04M
Name Market Value Shares Shares
Change
Shares
Change %
Janus Henderson Group
1
Janus Henderson Group
United Kingdom
$204M 20,788,363 +325,458 +2%
RCM
2
RA Capital Management
Massachusetts
$195M 19,889,683
SCM
3
Suvretta Capital Management
New York
$140M 14,210,000 -125,244 -0.9%
BlackRock
4
BlackRock
New York
$104M 10,569,424 +494,080 +5%
DTC
5
Deep Track Capital
Connecticut
$93.3M 9,500,000 +183,667 +2%
Vanguard Group
6
Vanguard Group
Pennsylvania
$80.9M 8,242,154 +1,078,545 +15%
ACA
7
Avoro Capital Advisors
New York
$66.3M 6,750,000 +400,000 +6%
State Street
8
State Street
Massachusetts
$41.7M 4,249,957 +219,650 +5%
Pictet Asset Management
9
Pictet Asset Management
Switzerland
$39.6M 4,035,390 -169,497 -4%
Citadel Advisors
10
Citadel Advisors
Florida
$37.7M 3,836,892 -1,249,944 -25%
Westfield Capital Management
11
Westfield Capital Management
Massachusetts
$33.1M 3,370,817 -523,924 -13%
Geode Capital Management
12
Geode Capital Management
Massachusetts
$30.6M 3,111,299 +213,325 +7%
Holocene Advisors
13
Holocene Advisors
New York
$30.1M 3,065,387 +3,065,387 New
PCH
14
Polar Capital Holdings
United Kingdom
$24.3M 2,475,000 -25,000 -1%
Point72 Asset Management
15
Point72 Asset Management
Connecticut
$22.3M 2,274,151 +2,274,151 New
Morgan Stanley
16
Morgan Stanley
New York
$21.5M 2,185,005 +1,555,776 +247%
Assenagon Asset Management
17
Assenagon Asset Management
Luxembourg
$21.3M 2,171,194 +1,742,299 +406%
SCM
18
Silverarc Capital Management
Massachusetts
$20M 2,037,087 +526,589 +35%
Adage Capital Partners
19
Adage Capital Partners
Massachusetts
$19.3M 1,969,000 +1,969,000 New
RI
20
RTW Investments
New York
$19.3M 1,967,527
EA
21
Emerald Advisers
Pennsylvania
$18.1M 1,844,370 +293,699 +19%
RG
22
Redmile Group
California
$15.2M 1,545,208 -341,236 -18%
Goldman Sachs
23
Goldman Sachs
New York
$12.3M 1,253,085 +257,636 +26%
Bank of America
24
Bank of America
North Carolina
$12.3M 1,249,954 +468,002 +60%
WP
25
Woodline Partners
California
$12M 1,222,661 +521,907 +74%