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Erasca
ERAS

225 hedge funds and large institutions have $4.39B invested in Erasca in 2026 Q1 according to their latest regulatory filings, with 97 funds opening new positions, 77 increasing their positions, 39 reducing their positions, and 23 closing their positions.

New
Increased
Maintained
Reduced
Closed

438% more capital invested

Capital invested by funds: $816M → $4.39B (+$3.57B)

336% more call options, than puts

Call options by funds: $41.4M | Put options by funds: $9.49M

322% more first-time investments, than exits

New positions opened: 97 | Existing positions closed: 23

200% more funds holding in top 10

Funds holding in top 10: 5 → 15 (+10)

97% more repeat investments, than reductions

Existing positions increased: 77 | Existing positions reduced: 39

46% more funds holding

Funds holding: 154 → 225 (+71)

10.7% more ownership

Funds ownership: 77.29% → 87.99% (+11%)

Holders
225
Holders Change
+71
Holders Change %
+46.1%
% of All Funds
2.77%
Holding in Top 10
15
Holding in Top 10 Change
+10
Holding in Top 10 Change %
+200%
% of All Funds
0.18%
New
97
Increased
77
Reduced
39
Closed
23
Calls
$41.4M
Puts
$9.49M
Net Calls
+$31.9M
Net Calls Change
+$21.2M

Top Buyers

1
RI
RTW Investments
New York
+$189M
2
CAM
Cormorant Asset Management
Massachusetts
+$68.6M
3
T. Rowe Price Investment Management
T. Rowe Price Investment Management
Maryland
+$60.8M
4
Balyasny Asset Management
Balyasny Asset Management
Illinois
+$59.6M
5
BlackRock
BlackRock
New York
+$53.8M

Top Sellers

1
SCM
Suvretta Capital Management
New York
-$131M
2
AVM
Arch Venture Management
Illinois
-$46.9M
3
PBA
Paradigm Biocapital Advisors
New York
-$44.5M
4
SSC
Spruce Street Capital
New York
-$41M
5
5VM
5AM Venture Management
California
-$22.7M
Name Holding Trade Value Shares
Change 		Change in
Stake
FLSM
1
Frazier Life Sciences Management
California
$399M +$23M +1,945,752 +9%
T. Rowe Price Investment Management
2
T. Rowe Price Investment Management
Maryland
$344M +$60.8M +5,148,232 +32%
BlackRock
3
BlackRock
New York
$326M +$53.8M +4,554,076 +29%
VA
4
VR Adviser
New York
$265M -$17.4M -1,474,271 -8%
RI
5
RTW Investments
New York
$261M +$189M +16,010,524 +10,917%
VC
6
Vivo Capital
California
$197M +$34M +2,878,052 +31%
VCM
7
Vanguard Capital Management
Pennsylvania
$182M +$133M +11,249,738 New
SL
8
Siren LLC
Connecticut
$182M +$29.4M +2,486,997 +28%
LGM
9
Logos Global Management
California
$180M -$21.9M -1,850,000 -14%
PBA
10
Paradigm Biocapital Advisors
New York
$168M -$44.5M -3,766,393 -27%
State Street
11
State Street
Massachusetts
$150M +$36.9M +3,125,442 +51%
AVM
12
Arch Venture Management
Illinois
$115M -$46.9M -3,963,997 -36%
Geode Capital Management
13
Geode Capital Management
Massachusetts
$97M +$12.6M +1,069,814 +22%
CAM
14
Cormorant Asset Management
Massachusetts
$93.8M +$68.6M +5,800,000 New
AAA
15
Affinity Asset Advisors
New York
$86.6M +$17.1M +1,450,000 +37%
Balyasny Asset Management
16
Balyasny Asset Management
Illinois
$83.2M +$59.6M +5,045,912 +5,145%
Goldman Sachs
17
Goldman Sachs
New York
$78.9M +$18.2M +1,543,768 +46%
Janus Henderson Group
18
Janus Henderson Group
United Kingdom
$60M +$43.9M +3,710,966 New
5VM
19
5AM Venture Management
California
$56.4M -$22.7M -1,919,433 -36%
SCM
20
Suvretta Capital Management
New York
$55.6M -$131M -11,067,037 -76%
CC
21
Commodore Capital
New York
$51.4M +$37.5M +3,175,000 New
Bank of America
22
Bank of America
North Carolina
$49.4M +$17.1M +1,444,047 +90%
ACM
23
AH Capital Management
California
$46.3M – – –
WP
24
Woodline Partners
California
$45.8M +$10.6M +900,896 +47%
Adage Capital Partners
25
Adage Capital Partners
Massachusetts
$34M +$24.8M +2,100,000 New
1
2 3 4 5

ERAS Hedge Fund Activity: Q1 2026 in Review

225 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Erasca (ERAS) for Q1 2026, worth a combined $4.39B — up 438% from $816M a quarter earlier.

Buyers outnumbered sellers: 97 funds opened new ERAS positions and 23 closed out — a net gain of 74 holders — while 77 added to existing stakes and 39 trimmed.

The largest buyer was RTW Investments, adding an estimated $189M. The largest seller was Suvretta Capital Management, cutting an estimated $131M.

  • 225 institutional investors held Erasca (ERAS) as of Q1 2026, up from 154 in Q4 2025.
  • Funds reported $4.39B of Erasca stock for Q1 2026, up 438% quarter-over-quarter.
  • 97 funds opened new Erasca positions in Q1 2026 and 23 closed out, a net change of +74 holders.
  • The largest Erasca buyer in Q1 2026 was RTW Investments, an estimated $189M added.
  • The largest Erasca seller in Q1 2026 was Suvretta Capital Management, an estimated $131M sold.

Based on aggregated 13F filings for Q1 2026.