|
1
|
RA Capital Management
Boston,
Massachusetts
|
$110M
|
+$9.38M
|
+546,259
|
+10%
|
|
|
2
|
Avoro Capital Advisors
New York
|
$94.2M
|
-$6.76M
|
-393,482
|
-7%
|
|
|
3
|
|
$93.7M
|
+$1.12M
|
+65,410
|
+1%
|
|
|
4
|
VHCP Management II
New York
|
$74.8M
|
-$1.52M
|
-88,698
|
-2%
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$62.6M
|
+$6.77M
|
+394,259
|
+13%
|
|
|
6
|
Deerfield Management
New York
|
$62.4M
|
+$20.4M
|
+1,189,785
|
+51%
|
|
|
7
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$57.9M
|
+$11M
|
+642,082
|
+25%
|
|
|
8
|
Baker Bros. Advisors
New York
|
$45.3M
|
+$4.64M
|
+270,270
|
+12%
|
|
|
9
|
Perceptive Advisors
New York
|
$43.4M
|
+$8.93M
|
+520,000
|
+27%
|
|
|
10
|
Point72 Asset Management
Stamford,
Connecticut
|
$37.4M
|
+$36.2M
|
+2,106,849
|
New
|
|
|
11
|
Janus Henderson Group
London,
|
$31.2M
|
+$30.2M
|
+1,758,435
|
New
|
|
|
12
|
State Street
Boston,
Massachusetts
|
$28.7M
|
+$832K
|
+48,436
|
+3%
|
|
|
13
|
Great Point Partners
Greenwich,
Connecticut
|
$28.5M
|
+$27.6M
|
+1,606,100
|
New
|
|
|
14
|
Citadel Advisors
Miami,
Florida
|
$24.2M
|
-$11M
|
-639,446
|
-32%
|
|
|
15
|
|
$24M
|
+$6.21M
|
+361,750
|
+37%
|
|
|
16
|
Eventide Asset Management
Boston,
Massachusetts
|
$23.3M
|
+$16.6M
|
+964,000
|
+275%
|
|
|
17
|
Adage Capital Partners
Boston,
Massachusetts
|
$21.3M
|
+$7.73M
|
+450,000
|
+60%
|
|
|
18
|
Ghost Tree Capital
New York
|
$19.5M
|
+$10.3M
|
+600,000
|
+120%
|
|
|
19
|
Fidelity Investments
Boston,
Massachusetts
|
$16.1M
|
+$255K
|
+14,827
|
+2%
|
|
|
20
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$15.1M
|
+$3M
|
+175,000
|
+26%
|
|
|
21
|
Schonfeld Strategic Advisors
New York
|
$14.6M
|
+$11.7M
|
+681,900
|
+486%
|
|
|
22
|
Northern Trust
Chicago,
Illinois
|
$14.2M
|
+$265K
|
+15,441
|
+2%
|
|
|
23
|
Geode Capital Management
Boston,
Massachusetts
|
$11.9M
|
+$1.13M
|
+65,708
|
+11%
|
|
|
24
|
Nexthera Capital
New York
|
$11.6M
|
+$1M
|
+58,532
|
+10%
|
|
|
25
|
VHCP Management III
New York
|
$10.7M
|
+$10.3M
|
+600,000
|
New
|
|
