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Dyne Therapeutics

205 hedge funds and large institutions have $1.29B invested in Dyne Therapeutics in 2025 Q1 according to their latest regulatory filings, with 49 funds opening new positions, 81 increasing their positions, 45 reducing their positions, and 43 closing their positions.

New
Increased
Maintained
Reduced
Closed

369% more call options, than puts

Call options by funds: $3.39M | Put options by funds: $724K

80% more repeat investments, than reductions

Existing positions increased: 81 | Existing positions reduced: 45

14% more first-time investments, than exits

New positions opened: 49 | Existing positions closed: 43

3% more funds holding

Funds holding: 200205 (+5)

1.83% less ownership

Funds ownership: 109.69%107.86% (-1.8%)

29% less funds holding in top 10

Funds holding in top 10: 75 (-2)

51% less capital invested

Capital invested by funds: $2.63B → $1.29B (-$1.34B)

Holders
205
Holders Change
+5
Holders Change %
+2.5%
% of All Funds
2.75%
Holding in Top 10
5
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-28.57%
% of All Funds
0.07%
New
49
Increased
81
Reduced
45
Closed
43
Calls
$3.39M
Puts
$724K
Net Calls
+$2.67M
Net Calls Change
+$9.39M
Name Holding Trade Value Shares
Change
Change in
Stake
Voloridge Investment Management
26
Voloridge Investment Management
Florida
$14.5M +$18.2M +1,269,410 +1,067%
T. Rowe Price Investment Management
27
T. Rowe Price Investment Management
Maryland
$12.2M +$16.7M +1,167,975 New
VC
28
Vivo Capital
California
$11.7M
O
29
OrbiMed
New York
$10.6M -$3.04M -212,469 -17%
Goldman Sachs
30
Goldman Sachs
New York
$10.4M +$5.24M +366,183 +58%
ACH
31
ArrowMark Colorado Holdings
Colorado
$9.39M -$490K -34,285 -4%
DM
32
Deerfield Management
New York
$8.5M +$5.39M +376,755 +86%
Northern Trust
33
Northern Trust
Illinois
$7.56M -$780K -54,551 -7%
SI
34
Sofinnova Investments
California
$7.5M -$5.07M -354,602 -33%
MAM
35
MPM Asset Management
Massachusetts
$7.14M
Qube Research & Technologies (QRT)
36
Qube Research & Technologies (QRT)
United Kingdom
$7.12M +$5.91M +413,459 +155%
BBA
37
Baker Bros. Advisors
New York
$7.03M
Charles Schwab
38
Charles Schwab
California
$6.84M -$191K -13,321 -2%
WP
39
Woodline Partners
California
$6.01M +$6.84K +478 +0.1%
RSCM
40
Rock Springs Capital Management
Maryland
$5.49M +$715K +49,971 +11%
WA
41
Wasatch Advisors
Utah
$5.35M +$2.72M +190,422 +59%
LGM
42
Logos Global Management
California
$5.23M +$715K +50,000 +11%
AG
43
Algert Global
California
$4.98M +$5.65M +395,084 +488%
CS
44
Candriam SCA
Luxembourg
$4.85M +$887K +61,973 +15%
IHAM
45
Integral Health Asset Management
New York
$4.71M +$4.29M +300,000 +200%
SG Americas Securities
46
SG Americas Securities
New York
$4.5M +$5.88M +411,015 +2,159%
IC
47
Ikarian Capital
Texas
$3.75M +$5.13M +358,837 New
UBS Group
48
UBS Group
Switzerland
$3.74M -$2.61M -182,358 -34%
NCM
49
Nantahala Capital Management
Connecticut
$3.61M +$4.94M +345,062 New
TI
50
Trexquant Investment
Connecticut
$3.5M +$2.99M +209,065 +167%

DYN Hedge Fund Activity: Q1 2025 in Review

205 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in Dyne Therapeutics (DYN) for Q1 2025, worth a combined $1.29B — down 51% from $2.63B a quarter earlier.

Buyers outnumbered sellers: 49 funds opened new DYN positions and 43 closed out — a net gain of 6 holders — while 81 added to existing stakes and 45 trimmed.

The largest buyer was RA Capital Management, adding an estimated $47.7M. The largest seller was Holocene Advisors, exiting entirely with an estimated $55.3M sold.

  • 205 institutional investors held Dyne Therapeutics (DYN) as of Q1 2025, up from 200 in Q4 2024.
  • Funds reported $1.29B of Dyne Therapeutics stock for Q1 2025, down 51% quarter-over-quarter.
  • 49 funds opened new Dyne Therapeutics positions in Q1 2025 and 43 closed out, a net change of +6 holders.
  • The largest Dyne Therapeutics buyer in Q1 2025 was RA Capital Management, an estimated $47.7M added.
  • The largest Dyne Therapeutics seller in Q1 2025 was Holocene Advisors, an estimated $55.3M sold.

Based on aggregated 13F filings for Q1 2025.