Dyne Therapeutics
207 hedge funds and large institutions have $1.97B invested in Dyne Therapeutics in 2025 Q3 according to their latest regulatory filings, with 39 funds opening new positions, 111 increasing their positions, 38 reducing their positions, and 27 closing their positions.
192% more repeat investments, than reductions
Existing positions increased: 111 | Existing positions reduced: 38
61% more capital invested
Capital invested by funds: $1.23B → $1.97B (+$747M)
44% more first-time investments, than exits
New positions opened: 39 | Existing positions closed: 27
17% more funds holding in top 10
Funds holding in top 10: 6 → 7 (+1)
5% more funds holding
Funds holding: 197 → 207 (+10)
3.61% less ownership
Funds ownership: 113.15% → 109.54% (-3.6%)
24% less call options, than puts
Call options by funds: $2.45M | Put options by funds: $3.22M
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Janus Henderson Group
London,
United Kingdom
|
+$60.5M |
| 2 |
Marshall Wace
London,
United Kingdom
|
+$29.3M |
| 3 |
Citadel Advisors
Miami,
Florida
|
+$28.2M |
| 4 |
Vanguard Group
Malvern,
Pennsylvania
|
+$24.1M |
| 5 |
VPC
Vestal Point Capital
New York
|
+$23.4M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
RCM
RA Capital Management
Boston,
Massachusetts
|
-$92.5M |
| 2 |
PA
Perceptive Advisors
New York
|
-$19.5M |
| 3 |
T. Rowe Price Associates
Baltimore,
Maryland
|
-$11.2M |
| 4 |
B
Braidwell
Stamford,
Connecticut
|
-$6.19M |
| 5 |
WP
Woodline Partners
San Francisco,
California
|
-$5.47M |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
|
1C
226
111 Capital
Paris,
France
| – | -$147K | -15,458 | Closed |
|
227
SG Americas Securities
New York
| – | -$122K | -12,768 | Closed |
|
|
BPC
228
Bryce Point Capital
Scarsdale,
New York
| – | -$115K | -12,055 | Closed |
|
|
TSS
229
Two Sigma Securities
New York
| – | -$108K | -11,377 | Closed |
|
|
PD
230
Point72 (DIFC)
Dubai,
United Arab Emirates
| – | -$70.9K | -7,451 | Closed |
|
|
CIAM
231
Caitong International Asset Management
Hong Kong
| – | -$12.5K | -1,308 | Closed |
|
|
KIM
232
Kestra Investment Management
Austin,
Texas
| – | -$1.44K | -151 | Closed |
|
|
BIG
233
Brooklyn Investment Group
Brooklyn,
New York
| – | -$1.15K | -121 | Closed |
|
|
FDCDDQ
234
Federation des caisses Desjardins du Quebec
Levis,
Quebec, Canada
| – | -$190 | -20 | Closed |
|
DYN Hedge Fund Activity: Q3 2025 in Review
207 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Dyne Therapeutics (DYN) for Q3 2025, worth a combined $1.97B — up 61% from $1.23B a quarter earlier.
Buyers outnumbered sellers: 39 funds opened new DYN positions and 27 closed out — a net gain of 12 holders — while 111 added to existing stakes and 38 trimmed.
The largest buyer was Janus Henderson Group, adding an estimated $60.5M. The largest seller was RA Capital Management, exiting entirely with an estimated $92.5M sold.
- 207 institutional investors held Dyne Therapeutics (DYN) as of Q3 2025, up from 197 in Q2 2025.
- Funds reported $1.97B of Dyne Therapeutics stock for Q3 2025, up 61% quarter-over-quarter.
- 39 funds opened new Dyne Therapeutics positions in Q3 2025 and 27 closed out, a net change of +12 holders.
- The largest Dyne Therapeutics buyer in Q3 2025 was Janus Henderson Group, an estimated $60.5M added.
- The largest Dyne Therapeutics seller in Q3 2025 was RA Capital Management, an estimated $92.5M sold.
Based on aggregated 13F filings for Q3 2025.