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DRRX

DURECT Corp
DRRX

Delisted

DRRX was delisted on the 10th of September, 2025.

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77 hedge funds and large institutions have $349M invested in DURECT Corp in 2019 Q4 according to their latest regulatory filings, with 15 funds opening new positions, 31 increasing their positions, 14 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed

229% more capital invested

Capital invested by funds: $106M → $349M (+$243M)

121% more repeat investments, than reductions

Existing positions increased: 31 | Existing positions reduced: 14

100% more funds holding in top 10

Funds holding in top 10: 2 → 4 (+2)

36% more first-time investments, than exits

New positions opened: 15 | Existing positions closed: 11

11% more call options, than puts

Call options by funds: $3.96M | Put options by funds: $3.57M

5% more funds holding

Funds holding: 73 → 77 (+4)

1.75% more ownership

Funds ownership: 3.02% → 4.78% (+1.8%)

Holders
77
Holders Change
+4
Holders Change %
+5.48%
% of All Funds
1.52%
Holding in Top 10
4
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+100%
% of All Funds
0.08%
New
15
Increased
31
Reduced
14
Closed
11
Calls
$3.96M
Puts
$3.57M
Net Calls
+$391K
Net Calls Change
+$527K

Top Buyers

Rank Fund Capital Flow
1
Millennium Management
Millennium Management
New York
+$5.8M
2
DC
Davenport & Co
Virginia
+$2.18M
3
Susquehanna International Group
Susquehanna International Group
Pennsylvania
+$1.52M
4
Two Sigma Investments
Two Sigma Investments
New York
+$1.16M
5
Vanguard Group
Vanguard Group
Pennsylvania
+$1.11M

Top Sellers

Rank Fund Capital Flow
1
ISL
Ingalls & Snyder LLC
New York
-$793K
2
OAM
Oxford Asset Management
United Kingdom
-$728K
3
Assenagon Asset Management
Assenagon Asset Management
Luxembourg
-$692K
4
WG
Winton Group
United Kingdom
-$503K
5
PP
Paloma Partners
Connecticut
-$436K
Name Holding Trade Value Shares
Change 		Change in
Stake
HIM
26
Hillsdale Investment Management
Ontario, Canada
$1.3M +$706K +34,280 New
Goldman Sachs
27
Goldman Sachs
New York
$1.19M +$390K +18,901 +153%
JP Morgan Chase
28
JP Morgan Chase
New York
$951K -$412K -19,985 -44%
WG
29
Winton Group
United Kingdom
$931K -$503K -24,419 -50%
Wells Fargo
30
Wells Fargo
California
$839K +$22.6K +1,097 +5%
Citadel Advisors
31
Citadel Advisors
Florida
$705K +$190K +9,240 +99%
Simplex Trading
32
Simplex Trading
Illinois
$654K +$355K +17,218 New
Group One Trading
33
Group One Trading
Illinois
$544K +$290K +14,086 +5,869%
State Street
34
State Street
Massachusetts
$534K +$67.8K +3,288 +31%
RMC
35
Regis Management Company
California
$510K – – –
Bank of New York Mellon
36
Bank of New York Mellon
New York
$504K – – –
Ameriprise
37
Ameriprise
Minnesota
$446K -$2.88K -140 -1%
Assenagon Asset Management
38
Assenagon Asset Management
Luxembourg
$377K -$692K -33,573 -77%
SG Americas Securities
39
SG Americas Securities
New York
$372K -$62 -3 -0%
AGM
40
Alpine Global Management
New York
$371K +$201K +9,768 New
T. Rowe Price Associates
41
T. Rowe Price Associates
Maryland
$342K – – –
CPA
42
Cowen Prime Advisors
New York
$333K +$1.03K +50 +0.6%
VF
43
Virtu Financial
New York
$330K -$150K -7,264 -46%
Charles Schwab
44
Charles Schwab
California
$322K +$88.4K +4,290 +103%
Squarepoint
45
Squarepoint
New York
$294K +$98.1K +4,761 +160%
LTFS
46
Ladenburg Thalmann Financial Services
Florida
$247K – – –
Brown Advisory
47
Brown Advisory
Maryland
$228K – – –
Barclays
48
Barclays
United Kingdom
$190K +$97.5K +4,729 +1,745%
TFA
49
Tobias Financial Advisors
Florida
$186K +$101K +4,898 New
Wolverine Trading
50
Wolverine Trading
Illinois
$159K +$92.9K +4,509 New
1
2
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DRRX Hedge Fund Activity: Q4 2019 in Review

77 of the 5,076 institutional investors tracked by Wall St. Rank reported a position in DURECT Corp (DRRX) for Q4 2019, worth a combined $349M — up 229% from $106M a quarter earlier.

Buyers outnumbered sellers: 15 funds opened new DRRX positions and 11 closed out — a net gain of 4 holders — while 31 added to existing stakes and 14 trimmed.

The largest buyer was Millennium Management, adding an estimated $5.8M. The largest seller was Ingalls & Snyder LLC, cutting an estimated $793K.

  • 77 institutional investors held DURECT Corp (DRRX) as of Q4 2019, up from 73 in Q3 2019.
  • Funds reported $349M of DURECT Corp stock for Q4 2019, up 229% quarter-over-quarter.
  • 15 funds opened new DURECT Corp positions in Q4 2019 and 11 closed out, a net change of +4 holders.
  • The largest DURECT Corp buyer in Q4 2019 was Millennium Management, an estimated $5.8M added.
  • The largest DURECT Corp seller in Q4 2019 was Ingalls & Snyder LLC, an estimated $793K sold.

Based on aggregated 13F filings for Q4 2019.