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Day One Biopharmaceuticals

174 hedge funds and large institutions have $560M invested in Day One Biopharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 26 funds opening new positions, 71 increasing their positions, 56 reducing their positions, and 34 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

less funds holding

Funds holding:

less ownership

Funds ownership:

24% less first-time investments, than exits

New positions opened: 26 | Existing positions closed: 34

25% less capital invested

Capital invested by funds: $746M → $560M (-$186M)

50% less funds holding in top 10

Funds holding in top 10: 21 (-1)

Holders
174
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$902K
Puts
$581K
Net Calls
Net Calls Change

Top Buyers

1 +$20M
2 +$4.96M
3 +$4.31M
4
Renaissance Technologies
Renaissance Technologies
New York
+$4.24M
5
Morgan Stanley
Morgan Stanley
New York
+$4.18M
Name Holding Trade Value Shares
Change
Change in
Stake
PNC Financial Services Group
151
PNC Financial Services Group
Pennsylvania
$2.73K
WTA
152
Washington Trust Advisors
Massachusetts
$2.22K
Daiwa Securities Group
153
Daiwa Securities Group
Japan
$2K
SPIA
154
Steward Partners Investment Advisory
New York
$1.95K
EWA
155
EverSource Wealth Advisors
Alabama
$1.92K
Osaic Holdings
156
Osaic Holdings
Arizona
$1.84K
S
157
SignatureFD
Georgia
$1.14K
PA
158
Parallel Advisors
California
$923
AF
159
Allworth Financial
California
$845
RIL
160
Rothschild Investment LLC
Illinois
$780
PWMG
161
Private Wealth Management Group
New Jersey
$572
SS
162
SBI Securities
Japan
$514
IA
163
IFP Advisors
Florida
$377
TWD
164
True Wealth Design
Ohio
$351
MPWT
165
MassMutual Private Wealth & Trust
Connecticut
$332
GTAM
166
Global Trust Asset Management
Florida
$325
GI
167
GAMMA Investing
California
$306
FFA
168
Farther Finance Advisors
California
$306
US Bancorp
169
US Bancorp
Minnesota
$156
GM
170
GeoWealth Management
Illinois
$150
SAM
171
Smartleaf Asset Management
Massachusetts
$32
CA
172
Clearstead Advisors
Ohio
$20
Jones Financial Companies
173
Jones Financial Companies
Missouri
$13
RCM
174
RA Capital Management
Massachusetts
ECM
175
Estuary Capital Management
Minnesota