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Day One Biopharmaceuticals

174 hedge funds and large institutions have $560M invested in Day One Biopharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 26 funds opening new positions, 71 increasing their positions, 56 reducing their positions, and 34 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

less funds holding

Funds holding:

less ownership

Funds ownership:

24% less first-time investments, than exits

New positions opened: 26 | Existing positions closed: 34

25% less capital invested

Capital invested by funds: $746M → $560M (-$186M)

50% less funds holding in top 10

Funds holding in top 10: 21 (-1)

Holders
174
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$902K
Puts
$581K
Net Calls
Net Calls Change

Top Buyers

1 +$20M
2 +$4.96M
3 +$4.31M
4
Renaissance Technologies
Renaissance Technologies
New York
+$4.24M
5
Morgan Stanley
Morgan Stanley
New York
+$4.18M
Name Holding Trade Value Shares
Change
Change in
Stake
Verition Fund Management
101
Verition Fund Management
Connecticut
$172K
SPA
102
Sherbrooke Park Advisers
New York
$162K
CC
103
Corton Capital
Ontario, Canada
$159K
XT
104
XTX Topco
Cayman Islands
$158K
Cetera Investment Advisers
105
Cetera Investment Advisers
Illinois
$154K
Janus Henderson Group
106
Janus Henderson Group
United Kingdom
$139K
PA
107
Profund Advisors
Maryland
$136K
CUAMC
108
China Universal Asset Management Company
China
$132K
IWC
109
Integrated Wealth Concepts
Massachusetts
$131K
VOYA Investment Management
110
VOYA Investment Management
Georgia
$127K
PCM
111
Prelude Capital Management
New York
$127K
ASRS
112
Arizona State Retirement System
Arizona
$125K
ProShare Advisors
113
ProShare Advisors
Maryland
$121K
Creative Planning
114
Creative Planning
Kansas
$120K
Carson Wealth (CWM LLC)
115
Carson Wealth (CWM LLC)
Nebraska
$118K
State Board of Administration of Florida Retirement System
116
State Board of Administration of Florida Retirement System
Florida
$116K
OF
117
Optimize Financial
California
$116K
Teacher Retirement System of Texas
118
Teacher Retirement System of Texas
Texas
$115K
PFSRSONJ
119
Police & Firemen's Retirement System of New Jersey
New Jersey
$115K
A
120
AlphaQuest
New York
$103K
Cerity Partners
121
Cerity Partners
New York
$93.7K
Lazard Asset Management
122
Lazard Asset Management
New York
$89K
New York State Common Retirement Fund
123
New York State Common Retirement Fund
New York
$78.9K
KK
124
KLP Kapitalforvaltning
Norway
$76.7K
VRS
125
Virginia Retirement Systems
Virginia
$76K