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Day One Biopharmaceuticals

174 hedge funds and large institutions have $560M invested in Day One Biopharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 26 funds opening new positions, 71 increasing their positions, 56 reducing their positions, and 34 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

less funds holding

Funds holding:

less ownership

Funds ownership:

24% less first-time investments, than exits

New positions opened: 26 | Existing positions closed: 34

25% less capital invested

Capital invested by funds: $746M → $560M (-$186M)

50% less funds holding in top 10

Funds holding in top 10: 21 (-1)

Holders
174
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$902K
Puts
$581K
Net Calls
Net Calls Change

Top Buyers

1 +$20M
2 +$4.96M
3 +$4.31M
4
Renaissance Technologies
Renaissance Technologies
New York
+$4.24M
5
Morgan Stanley
Morgan Stanley
New York
+$4.18M
Name Holding Trade Value Shares
Change
Change in
Stake
AllianceBernstein
76
AllianceBernstein
Tennessee
$441K
VIA
77
Virtus Investment Advisers
Connecticut
$432K
GCP
78
GSA Capital Partners
United Kingdom
$413K
NRD
79
Nebula Research & Development
New York
$394K
DS
80
DRW Securities
Illinois
$376K
Legal & General Group
81
Legal & General Group
United Kingdom
$370K
Man Group
82
Man Group
United Kingdom
$370K
California State Teachers Retirement System (CalSTRS)
83
California State Teachers Retirement System (CalSTRS)
California
$365K
AA
84
ALPS Advisors
Colorado
$356K
EAM
85
Erste Asset Management
Austria
$331K
DC
86
Diametric Capital
Massachusetts
$325K
IIM
87
INTECH Investment Management
Florida
$295K
MIM
88
MetLife Investment Management
New Jersey
$289K
Mirae Asset Global ETFs Holdings
89
Mirae Asset Global ETFs Holdings
Hong Kong
$287K
Manulife (Manufacturers Life Insurance)
90
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$248K
Tudor Investment Corp
91
Tudor Investment Corp
Connecticut
$237K
MAM
92
Martingale Asset Management
Massachusetts
$228K
PFCS
93
Pale Fire Capital SE
Czech Republic
$226K
DMKJ
94
David M. Knott Jr
$219K
Zurich Cantonal Bank
95
Zurich Cantonal Bank
Switzerland
$214K
BCM
96
Bayesian Capital Management
New York
$183K
ACM
97
ADAR1 Capital Management
Texas
$182K
IC
98
IEQ Capital
California
$182K
American Century Companies
99
American Century Companies
Missouri
$178K
Verition Fund Management
100
Verition Fund Management
Connecticut
$172K