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Day One Biopharmaceuticals
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Overview Fund Activity

164 hedge funds and large institutions have $1.19B invested in Day One Biopharmaceuticals in 2024 Q4 according to their latest regulatory filings, with 33 funds opening new positions, 62 increasing their positions, 39 reducing their positions, and 33 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
164
Holders Change
-1
Holders Change %
-0.61%
% of All Funds
2.18%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.03%
New
33
Increased
62
Reduced
39
Closed
33
Calls
$2.08M
Puts
$3.36M
Net Calls
-$1.28M
Net Calls Change
+$713K

Top Buyers

1
Fidelity Investments
Fidelity Investments
Massachusetts
$163M
2
Alyeska Investment Group
Alyeska Investment Group
Illinois
$31.8M
3
BlackRock
BlackRock
New York
$78M
4
Marshall Wace
Marshall Wace
United Kingdom
$13.9M
5
ECM
Estuary Capital Management
Minnesota
$47.1M

Top Sellers

1
Viking Global Investors
Viking Global Investors
Connecticut
$0
2
MC
Maverick Capital
Texas
$0
3
RCM
RA Capital Management
Massachusetts
$72.9M
4
Goldman Sachs
Goldman Sachs
New York
$5.98M
5
VPC
Vestal Point Capital
New York
$18.2M
Name Holding Trade Value Shares
Change 		Shares
Change %
EC
26
EcoR1 Capital
California
$10.9M – – –
Adage Capital Partners
27
Adage Capital Partners
Massachusetts
$10.1M -$1.27M -100,000 -11%
WP
28
Woodline Partners
California
$10.1M +$20.2K +1,592 +0.2%
DCM
29
DAFNA Capital Management
California
$9.27M -$241K -19,000 -3%
Wellington Management Group
30
Wellington Management Group
Massachusetts
$9.27M +$123K +9,722 +1%
FLSM
31
Frazier Life Sciences Management
California
$8.74M – – –
Citadel Advisors
32
Citadel Advisors
Florida
$7.75M +$1.61M +127,052 +26%
Northern Trust
33
Northern Trust
Illinois
$6.93M +$658K +51,960 +10%
Charles Schwab
34
Charles Schwab
California
$6.78M +$355K +28,053 +6%
Goldman Sachs
35
Goldman Sachs
New York
$5.98M -$16.5M -1,302,068 -73%
Deutsche Bank
36
Deutsche Bank
Germany
$4.55M +$449K +35,460 +11%
SFM
37
Sphera Funds Management
Israel
$4.24M -$160K -12,640 -4%
PL
38
Parkwood LLC
Ohio
$3.48M +$3.48M +275,000 New
Two Sigma Investments
39
Two Sigma Investments
New York
$3.44M -$1.72M -135,725 -33%
Bank of New York Mellon
40
Bank of New York Mellon
New York
$3.1M +$939K +74,091 +43%
Renaissance Technologies
41
Renaissance Technologies
New York
$3.09M +$1.89M +148,900 +157%
SCM
42
Stonepine Capital Management
Oregon
$2.98M +$372K +29,325 +14%
ECM
43
ExodusPoint Capital Management
New York
$2.73M +$2.73M +215,137 New
EIM
44
Essex Investment Management
Massachusetts
$2.63M +$296K +23,344 +13%
KCM
45
Kennedy Capital Management
Missouri
$2.46M +$58.5K +4,615 +2%
Millennium Management
46
Millennium Management
New York
$2.43M +$1.08M +85,606 +80%
PCH
47
Polar Capital Holdings
United Kingdom
$2.34M – – –
Qube Research & Technologies (QRT)
48
Qube Research & Technologies (QRT)
United Kingdom
$2.34M +$1.2M +94,468 +105%
BC
49
BIT Capital
Germany
$2.18M +$641K +50,626 +42%
Norges Bank
50
Norges Bank
Norway
$2.14M +$2.14M +169,000 New
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