|
1
|
|
$51.2M
|
–
|
–
|
–
|
|
|
2
|
Novo Holdings A/S
Hellerup,
Denmark
|
$37.9M
|
–
|
–
|
–
|
|
|
3
|
Adams Street Partners
Chicago,
Illinois
|
$28.1M
|
–
|
–
|
–
|
|
|
4
|
Fidelity Investments
Boston,
Massachusetts
|
$17.3M
|
-$4.59M
|
-459,485
|
-19%
|
|
|
5
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$17.1M
|
-$119K
|
-11,926
|
-0.6%
|
|
|
6
|
BVF Inc
San Francisco,
California
|
$16.2M
|
–
|
–
|
–
|
|
|
7
|
|
$10.3M
|
+$870K
|
+87,013
|
+8%
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$5.82M
|
+$136K
|
+13,578
|
+2%
|
|
|
9
|
|
$5.05M
|
+$543K
|
+54,309
|
+10%
|
|
|
10
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$4.93M
|
–
|
–
|
–
|
|
|
11
|
Renaissance Technologies
New York
|
$3.4M
|
+$720K
|
+72,000
|
+22%
|
|
|
12
|
EcoR1 Capital
San Francisco,
California
|
$3.02M
|
-$990K
|
-98,999
|
-22%
|
|
|
13
|
Sphera Funds Management
Tel Aviv,
Israel
|
$2.76M
|
-$146K
|
-14,557
|
-4%
|
|
|
14
|
Dimensional Fund Advisors
Austin,
Texas
|
$2.24M
|
+$1.04M
|
+104,230
|
+67%
|
|
|
15
|
State Street
Boston,
Massachusetts
|
$1.57M
|
+$166K
|
+16,586
|
+10%
|
|
|
16
|
Northern Trust
Chicago,
Illinois
|
$1.3M
|
+$17K
|
+1,696
|
+1%
|
|
|
17
|
Geode Capital Management
Boston,
Massachusetts
|
$1.1M
|
+$46.9K
|
+4,686
|
+4%
|
|
|
18
|
|
$1.01M
|
+$30K
|
+2,997
|
+3%
|
|
|
19
|
Bridgeway Capital Management
Houston,
Texas
|
$897K
|
+$196K
|
+19,600
|
+23%
|
|
|
20
|
International Biotechnology Trust
London,
United Kingdom
|
$710K
|
+$267K
|
+26,659
|
+33%
|
|
|
21
|
Oxford Asset Management
Oxford,
United Kingdom
|
$550K
|
+$89K
|
+8,902
|
+16%
|
|
|
22
|
Bank of America
Charlotte,
North Carolina
|
$522K
|
+$68.1K
|
+6,813
|
+13%
|
|
|
23
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$509K
|
+$246K
|
+24,636
|
+71%
|
|
|
24
|
|
$436K
|
+$358K
|
+35,771
|
+238%
|
|
|
25
|
Connor, Clark & Lunn Investment Management (CC&L)
Vancouver,
British Columbia, Canada
|
$414K
|
+$6.5K
|
+650
|
+1%
|
|
