|
1
|
|
$65.5M
|
–
|
–
|
–
|
|
|
2
|
Novo Holdings A/S
Hellerup,
Denmark
|
$48.5M
|
–
|
–
|
–
|
|
|
3
|
Adams Street Partners
Chicago,
Illinois
|
$36M
|
–
|
–
|
–
|
|
|
4
|
Fidelity Investments
Boston,
Massachusetts
|
$27.2M
|
-$824K
|
-73,823
|
-3%
|
|
|
5
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$22M
|
-$51.1K
|
-4,576
|
-0.2%
|
|
|
6
|
BVF Inc
San Francisco,
California
|
$20.8M
|
-$712K
|
-63,747
|
-3%
|
|
|
7
|
|
$12.3M
|
+$4.27M
|
+382,389
|
+52%
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$7.29M
|
+$596K
|
+53,375
|
+9%
|
|
|
9
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$6.31M
|
–
|
–
|
–
|
|
|
10
|
|
$5.87M
|
+$5.97M
|
+534,397
|
New
|
|
|
11
|
EcoR1 Capital
San Francisco,
California
|
$4.95M
|
-$215K
|
-19,300
|
-4%
|
|
|
12
|
Millennium Management
New York
|
$3.79M
|
-$2.9M
|
-259,729
|
-43%
|
|
|
13
|
Sphera Funds Management
Tel Aviv,
Israel
|
$3.69M
|
+$162K
|
+14,557
|
+5%
|
|
|
14
|
Renaissance Technologies
New York
|
$3.57M
|
-$1.14M
|
-101,800
|
-24%
|
|
|
15
|
State Street
Boston,
Massachusetts
|
$1.83M
|
+$783K
|
+70,159
|
+73%
|
|
|
16
|
Dimensional Fund Advisors
Austin,
Texas
|
$1.72M
|
+$246K
|
+22,035
|
+16%
|
|
|
17
|
Northern Trust
Chicago,
Illinois
|
$1.65M
|
+$684K
|
+61,276
|
+69%
|
|
|
18
|
Geode Capital Management
Boston,
Massachusetts
|
$1.35M
|
+$529K
|
+47,391
|
+62%
|
|
|
19
|
|
$1.26M
|
-$1.16M
|
-103,681
|
-48%
|
|
|
20
|
Bridgeway Capital Management
Houston,
Texas
|
$933K
|
–
|
–
|
–
|
|
|
21
|
International Biotechnology Trust
London,
United Kingdom
|
$892K
|
+$908K
|
+81,341
|
New
|
|
|
22
|
|
$856K
|
+$477K
|
+42,770
|
+121%
|
|
|
23
|
Oxford Asset Management
Oxford,
United Kingdom
|
$607K
|
+$18.8K
|
+1,682
|
+3%
|
|
|
24
|
Bank of America
Charlotte,
North Carolina
|
$593K
|
+$15.2K
|
+1,358
|
+3%
|
|
|
25
|
Connor, Clark & Lunn Investment Management (CC&L)
Vancouver,
British Columbia, Canada
|
$523K
|
+$32.4K
|
+2,900
|
+6%
|
|
