|
1
|
Essex Woodlands Management
The Woodlands,
Texas
|
$3.36M
|
-$110M
|
-9,353,304
|
Closed
|
|
|
2
|
Teachers Advisors
New York
|
$9K
|
–
|
–
|
–
|
|
|
3
|
TIAA CREF Investment Management
New York
|
$8K
|
–
|
–
|
–
|
|
|
4
|
Tower Research Capital (TRC)
New York
|
$2K
|
-$45.5K
|
-3,866
|
-96%
|
|
|
5
|
Perceptive Advisors
New York
|
–
|
-$60.5M
|
-6,357,133
|
Closed
|
|
|
6
|
|
–
|
-$34.3M
|
-3,610,632
|
Closed
|
|
|
7
|
Broadfin Capital
New York
|
–
|
-$22.5M
|
-2,368,557
|
Closed
|
|
|
8
|
AWM Investment Company
New York
|
–
|
-$21.5M
|
-2,264,661
|
Closed
|
|
|
9
|
|
–
|
-$21.3M
|
-2,242,514
|
Closed
|
|
|
10
|
Franklin Resources
San Mateo,
California
|
–
|
-$19.6M
|
-2,065,461
|
Closed
|
|
|
11
|
Vanguard Group
Malvern,
Pennsylvania
|
–
|
-$13.7M
|
-1,442,564
|
Closed
|
|
|
12
|
Tamarack Advisers
Carlsbad,
California
|
–
|
-$13.6M
|
-1,425,000
|
Closed
|
|
|
13
|
Opaleye Management
Boston,
Massachusetts
|
–
|
-$5.23M
|
-550,000
|
Closed
|
|
|
14
|
|
–
|
-$4.89M
|
-514,516
|
Closed
|
|
|
15
|
Royce & Associates
New York
|
–
|
-$4.78M
|
-502,564
|
Closed
|
|
|
16
|
State Street
Boston,
Massachusetts
|
–
|
-$4.21M
|
-442,571
|
Closed
|
|
|
17
|
UBS Group
Zurich,
Switzerland
|
–
|
-$3.58M
|
-376,721
|
Closed
|
|
|
18
|
Gilder Gagnon Howe & Co
New York
|
–
|
-$3.18M
|
-334,468
|
Closed
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
–
|
-$3.11M
|
-327,207
|
Closed
|
|
|
20
|
|
–
|
-$2.77M
|
-291,474
|
Closed
|
|
|
21
|
Geode Capital Management
Boston,
Massachusetts
|
–
|
-$2.73M
|
-286,746
|
Closed
|
|
|
22
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
–
|
-$2.24M
|
-236,000
|
Closed
|
|
|
23
|
Needham Investment Management
New York
|
–
|
-$1.98M
|
-208,141
|
Closed
|
|
|
24
|
Two Sigma Investments
New York
|
–
|
-$1.93M
|
-203,230
|
Closed
|
|
|
25
|
Essex Investment Management
Boston,
Massachusetts
|
–
|
-$1.62M
|
-170,006
|
Closed
|
|
