|
1
|
Essex Woodlands Management
The Woodlands,
Texas
|
$69.8M
|
–
|
–
|
–
|
|
|
2
|
Perceptive Advisors
New York
|
$43.6M
|
+$19M
|
+3,192,648
|
+120%
|
|
|
3
|
Broadfin Capital
New York
|
$33.1M
|
+$9.81M
|
+1,649,605
|
+59%
|
|
|
4
|
AWM Investment Company
New York
|
$17M
|
-$1.04M
|
-175,000
|
-7%
|
|
|
5
|
|
$12.2M
|
+$1.09M
|
+183,010
|
+13%
|
|
|
6
|
Tamarack Advisers
Carlsbad,
California
|
$7.27M
|
-$523K
|
-88,000
|
-8%
|
|
|
7
|
|
$6.83M
|
+$4.79M
|
+805,422
|
+731%
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$6.65M
|
+$2.32M
|
+390,330
|
+78%
|
|
|
9
|
Franklin Resources
San Mateo,
California
|
$6.56M
|
+$5.35K
|
+900
|
+0.1%
|
|
|
10
|
Senzar Asset Management
New York
|
$6M
|
-$4.19M
|
-704,500
|
-47%
|
|
|
11
|
Opaleye Management
Boston,
Massachusetts
|
$5.33M
|
+$3.29M
|
+553,000
|
+341%
|
|
|
12
|
Needham Investment Management
New York
|
$4.51M
|
-$128K
|
-21,475
|
-3%
|
|
|
13
|
Royce & Associates
New York
|
$3.25M
|
-$674K
|
-113,400
|
-21%
|
|
|
14
|
Stonepine Capital Management
Bend,
Oregon
|
$3.08M
|
+$2.46M
|
+413,568
|
New
|
|
|
15
|
State Street
Boston,
Massachusetts
|
$1.84M
|
+$1.47M
|
+246,694
|
New
|
|
|
16
|
Northern Trust
Chicago,
Illinois
|
$1.72M
|
+$1.15M
|
+193,554
|
+523%
|
|
|
17
|
Essex Investment Management
Boston,
Massachusetts
|
$1.44M
|
+$629K
|
+105,706
|
+121%
|
|
|
18
|
Bridgeway Capital Management
Houston,
Texas
|
$1.41M
|
+$15.5K
|
+2,600
|
+1%
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$1.39M
|
+$693K
|
+116,518
|
+168%
|
|
|
20
|
Renaissance Technologies
New York
|
$1.35M
|
+$1.08M
|
+181,400
|
New
|
|
|
21
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$1.12M
|
+$896K
|
+150,677
|
New
|
|
|
22
|
Iguana Healthcare Management
New York
|
$746K
|
+$595K
|
+100,000
|
New
|
|
|
23
|
EAM Investors
Solana Beach,
California
|
$563K
|
+$449K
|
+75,473
|
New
|
|
|
24
|
Two Sigma Investments
New York
|
$509K
|
+$405K
|
+68,192
|
New
|
|
|
25
|
Bank of New York Mellon
New York
|
$494K
|
+$243K
|
+40,891
|
+162%
|
|
