CNTA

Centessa Pharmaceuticals
CNTA

Overview Fund Activity

117 hedge funds and large institutions have $1.62B invested in Centessa Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 19 funds opening new positions, 45 increasing their positions, 34 reducing their positions, and 31 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
117
Holders Change
-12
Holders Change %
-9.3%
% of All Funds
1.57%
Holding in Top 10
10
Holding in Top 10 Change
-4
Holding in Top 10 Change %
-28.57%
% of All Funds
0.13%
New
19
Increased
45
Reduced
34
Closed
31
Calls
$8.54M
Puts
$2.02M
Net Calls
+$6.52M
Net Calls Change
+$15.9M

Top Buyers

1
RI
RTW Investments
New York
+$19.4M
2
Adage Capital Partners
Adage Capital Partners
Massachusetts
+$19M
3
Balyasny Asset Management
Balyasny Asset Management
Illinois
+$16.1M
4
Millennium Management
Millennium Management
New York
+$13.8M
5
PCH
Polar Capital Holdings
United Kingdom
+$13.1M

Top Sellers

1
Holocene Advisors
Holocene Advisors
New York
-$32.4M
2
T. Rowe Price Investment Management
T. Rowe Price Investment Management
Maryland
-$26.2M
3
PA
Perceptive Advisors
New York
-$24.9M
4
BBA
Baker Bros. Advisors
New York
-$17.6M
5
Morgan Stanley
Morgan Stanley
New York
-$15M
Name Holding Trade Value Shares
Change 		Shares
Change %
MVM
1
Medicxi Ventures Management
Jersey
$262M – – –
IVLAV
2
Index Venture Life Associates VI
Jersey
$131M – – –
GA
3
General Atlantic
New York
$127M – – –
Adage Capital Partners
4
Adage Capital Partners
Massachusetts
$110M +$19M +1,449,000 +21%
Janus Henderson Group
5
Janus Henderson Group
United Kingdom
$85.8M +$8.02M +610,282 +10%
T. Rowe Price Associates
6
T. Rowe Price Associates
Maryland
$77.6M +$7.43M +565,648 +11%
ACA
7
Avoro Capital Advisors
New York
$65.7M +$12.5M +950,000 +23%
FCM
8
Farallon Capital Management
California
$59.5M +$2.56M +195,000 +4%
FLAM
9
First Light Asset Management
Minnesota
$56.4M -$7.63M -580,713 -12%
Fidelity Investments
10
Fidelity Investments
Massachusetts
$50.3M – – –
SL
11
Siren LLC
Connecticut
$45.5M +$6.57M +500,000 +17%
CC
12
Commodore Capital
New York
$43.3M +$12.2M +930,711 +39%
TCM
13
TCG Crossover Management
California
$38M – – –
Point72 Asset Management
14
Point72 Asset Management
Connecticut
$34.1M +$4.01M +305,163 +13%
Franklin Resources
15
Franklin Resources
California
$33.4M +$20.2K +1,540 +0.1%
CAM
16
Cormorant Asset Management
Massachusetts
$27.4M -$2.3M -175,000 -8%
Morgan Stanley
17
Morgan Stanley
New York
$23.6M -$15M -1,143,996 -39%
Millennium Management
18
Millennium Management
New York
$21.8M +$13.8M +1,048,699 +172%
RI
19
RTW Investments
New York
$20.1M +$19.4M +1,479,836 +2,960%
SC
20
Stempoint Capital
New York
$16.6M +$8.83M +672,337 +113%
FCMV
21
Foresite Capital Management VI
California
$16.5M – – –
Balyasny Asset Management
22
Balyasny Asset Management
Illinois
$16.1M +$16.1M +1,221,610 New
PA
23
Perceptive Advisors
New York
$15.1M -$24.9M -1,893,460 -62%
American Century Companies
24
American Century Companies
Missouri
$14.9M +$499K +37,954 +3%
OCA
25
Octagon Capital Advisors
New York
$13.5M -$5.19M -395,000 -28%
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