CNTA

Centessa Pharmaceuticals
CNTA

Overview Fund Activity

129 hedge funds and large institutions have $1.8B invested in Centessa Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 31 funds opening new positions, 42 increasing their positions, 38 reducing their positions, and 15 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
129
Holders Change
+15
Holders Change %
+13.16%
% of All Funds
1.75%
Holding in Top 10
14
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+16.67%
% of All Funds
0.19%
New
31
Increased
42
Reduced
38
Closed
15
Calls
$2.37M
Puts
$11.7M
Net Calls
-$9.36M
Net Calls Change
-$5.79M

Top Buyers

1
ACA
Avoro Capital Advisors
New York
+$58.2M
2
Holocene Advisors
Holocene Advisors
New York
+$32.4M
3
Adage Capital Partners
Adage Capital Partners
Massachusetts
+$26.4M
4
Janus Henderson Group
Janus Henderson Group
United Kingdom
+$14.8M
5
Morgan Stanley
Morgan Stanley
New York
+$14.6M

Top Sellers

1
VVA
Vida Ventures Advisors
Massachusetts
-$65.9M
2
PA
Perceptive Advisors
New York
-$47.6M
3
T. Rowe Price Investment Management
T. Rowe Price Investment Management
Maryland
-$23.9M
4
DTC
Deep Track Capital
Connecticut
-$22.6M
5
Point72 Asset Management
Point72 Asset Management
Connecticut
-$16.4M
Name Holding Trade Value Shares
Change 		Shares
Change %
MVM
1
Medicxi Ventures Management
Jersey
$287M – – –
IVLAV
2
Index Venture Life Associates VI
Jersey
$143M – – –
GA
3
General Atlantic
New York
$139M – – –
Adage Capital Partners
4
Adage Capital Partners
Massachusetts
$100M +$26.4M +1,834,973 +36%
Janus Henderson Group
5
Janus Henderson Group
United Kingdom
$86.4M +$14.8M +1,012,999 +21%
T. Rowe Price Associates
6
T. Rowe Price Associates
Maryland
$76.8M -$317K -22,048 -0.4%
FLAM
7
First Light Asset Management
Minnesota
$70.1M -$13.4M -931,060 -16%
FCM
8
Farallon Capital Management
California
$62.3M +$12M +835,609 +24%
ACA
9
Avoro Capital Advisors
New York
$58.2M +$58.2M +4,050,000 New
Fidelity Investments
10
Fidelity Investments
Massachusetts
$55M +$2.51M +174,600 +5%
PA
11
Perceptive Advisors
New York
$43.7M -$47.6M -3,308,825 -52%
SL
12
Siren LLC
Connecticut
$42.6M -$642K -44,648 -1%
Morgan Stanley
13
Morgan Stanley
New York
$42.2M +$14.6M +1,012,958 +53%
TCM
14
TCG Crossover Management
California
$41.6M – – –
Franklin Resources
15
Franklin Resources
California
$36.6M +$3.36M +233,453 +10%
CC
16
Commodore Capital
New York
$34M +$2.14M +149,153 +7%
Point72 Asset Management
17
Point72 Asset Management
Connecticut
$32.9M -$16.4M -1,140,166 -33%
CAM
18
Cormorant Asset Management
Massachusetts
$32.5M -$4.31M -300,000 -12%
Holocene Advisors
19
Holocene Advisors
New York
$32.4M +$32.4M +2,255,679 New
T. Rowe Price Investment Management
20
T. Rowe Price Investment Management
Maryland
$25.2M -$23.9M -1,665,352 -49%
AAA
21
Affinity Asset Advisors
New York
$22.2M +$6.48M +450,738 +41%
OCA
22
Octagon Capital Advisors
New York
$20.5M -$8.17M -568,052 -29%
FCMV
23
Foresite Capital Management VI
California
$18M – – –
BBA
24
Baker Bros. Advisors
New York
$17.6M – – –
DCM
25
Driehaus Capital Management
Illinois
$15.8M -$7.23M -502,650 -31%
1
2 3 4 5