|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$31.9M
|
+$71.2K
|
+15,079
|
+0.2%
|
|
|
2
|
Redmile Group
San Francisco,
California
|
$15.4M
|
+$619K
|
+131,013
|
+4%
|
|
|
3
|
Numeric Investors
Boston,
Massachusetts
|
$8.14M
|
-$1.05M
|
-221,625
|
-11%
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$7.52M
|
+$579K
|
+122,637
|
+8%
|
|
|
5
|
BlackRock Fund Advisors
San Francisco,
California
|
$6.58M
|
-$1.92M
|
-407,547
|
-22%
|
|
|
6
|
EcoR1 Capital
San Francisco,
California
|
$6.51M
|
+$3.86M
|
+817,625
|
+137%
|
|
|
7
|
Opaleye Management
Boston,
Massachusetts
|
$5.38M
|
+$1.84M
|
+390,000
|
+50%
|
|
|
8
|
BlackRock Institutional Trust
San Francisco,
California
|
$5.03M
|
-$16.7K
|
-3,530
|
-0.3%
|
|
|
9
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$4.81M
|
+$1.06M
|
+223,495
|
+27%
|
|
|
10
|
State Street
Boston,
Massachusetts
|
$3.45M
|
+$88.2K
|
+18,688
|
+3%
|
|
|
11
|
Millennium Management
New York
|
$2.85M
|
+$1.77M
|
+374,347
|
+152%
|
|
|
12
|
Northern Trust
Chicago,
Illinois
|
$2.74M
|
+$16.7K
|
+3,531
|
+0.6%
|
|
|
13
|
|
$2.53M
|
+$426K
|
+90,206
|
+20%
|
|
|
14
|
|
$2.48M
|
-$31.6K
|
-6,694
|
-1%
|
|
|
15
|
|
$2.3M
|
–
|
–
|
–
|
|
|
16
|
Dimensional Fund Advisors
Austin,
Texas
|
$2.23M
|
+$1.51M
|
+320,353
|
+194%
|
|
|
17
|
|
$2.18M
|
–
|
–
|
–
|
|
|
18
|
Rhenman & Partners Asset Management
Stockholm,
Sweden
|
$1.84M
|
-$708K
|
-150,000
|
-27%
|
|
|
19
|
Acadian Asset Management
Boston,
Massachusetts
|
$1.52M
|
+$771K
|
+163,289
|
+98%
|
|
|
20
|
Bogle Investment Management
Newton Lower Falls,
Massachusetts
|
$1.45M
|
-$602K
|
-127,423
|
-29%
|
|
|
21
|
Tekla Capital Management
Boston,
Massachusetts
|
$1.42M
|
–
|
–
|
–
|
|
|
22
|
Geode Capital Management
Boston,
Massachusetts
|
$1.41M
|
+$47.3K
|
+10,025
|
+3%
|
|
|
23
|
Two Sigma Investments
New York
|
$1.33M
|
+$674K
|
+142,697
|
+97%
|
|
|
24
|
Panagora Asset Management
Boston,
Massachusetts
|
$1.32M
|
-$3.74K
|
-792
|
-0.3%
|
|
|
25
|
GSA Capital Partners
London,
United Kingdom
|
$1.2M
|
+$343K
|
+72,758
|
+39%
|
|
