|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$27.2M
|
+$22.7K
|
+4,593
|
+0.1%
|
|
|
2
|
Redmile Group
San Francisco,
California
|
$12.9M
|
+$16.2M
|
+3,288,376
|
New
|
|
|
3
|
Numeric Investors
Boston,
Massachusetts
|
$8.15M
|
+$3.62M
|
+732,604
|
+55%
|
|
|
4
|
BlackRock Fund Advisors
San Francisco,
California
|
$6.63M
|
-$16K
|
-3,233
|
-0.2%
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$6.43M
|
-$2.83M
|
-572,984
|
-26%
|
|
|
6
|
Jennison Associates
New York
|
$5.04M
|
-$7.24K
|
-1,466
|
-0.1%
|
|
|
7
|
BlackRock Institutional Trust
San Francisco,
California
|
$4.41M
|
-$56.9K
|
-11,519
|
-1%
|
|
|
8
|
|
$3.9M
|
-$11.2M
|
-2,264,710
|
-70%
|
|
|
9
|
Millennium Management
New York
|
$3.63M
|
-$1.46M
|
-294,578
|
-24%
|
|
|
10
|
State Street
Boston,
Massachusetts
|
$2.86M
|
-$81.1K
|
-16,415
|
-2%
|
|
|
11
|
Opaleye Management
Boston,
Massachusetts
|
$2.65M
|
–
|
–
|
–
|
|
|
12
|
Farallon Capital Management
San Francisco,
California
|
$2.33M
|
-$503K
|
-101,862
|
-15%
|
|
|
13
|
Rhenman & Partners Asset Management
Stockholm,
Sweden
|
$2.16M
|
+$247K
|
+50,000
|
+10%
|
|
|
14
|
Northern Trust
Chicago,
Illinois
|
$2M
|
+$70.5K
|
+14,262
|
+3%
|
|
|
15
|
Bogle Investment Management
Newton Lower Falls,
Massachusetts
|
$1.95M
|
+$2.45M
|
+496,676
|
New
|
|
|
16
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$1.9M
|
-$2.25M
|
-454,950
|
-48%
|
|
|
17
|
Two Sigma Investments
New York
|
$1.86M
|
+$660K
|
+133,532
|
+39%
|
|
|
18
|
|
$1.86M
|
–
|
–
|
–
|
|
|
19
|
Panagora Asset Management
Boston,
Massachusetts
|
$1.84M
|
+$2.31M
|
+467,870
|
New
|
|
|
20
|
Tekla Capital Management
Boston,
Massachusetts
|
$1.21M
|
–
|
–
|
–
|
|
|
21
|
Geode Capital Management
Boston,
Massachusetts
|
$1.14M
|
+$18.8K
|
+3,812
|
+1%
|
|
|
22
|
Renaissance Technologies
New York
|
$1.04M
|
-$1.85M
|
-375,123
|
-59%
|
|
|
23
|
TIAA CREF Investment Management
New York
|
$894K
|
+$191K
|
+38,693
|
+20%
|
|
|
24
|
|
$869K
|
+$251K
|
+50,736
|
+30%
|
|
|
25
|
FT Options
Chicago,
Illinois
|
$866K
|
-$333K
|
-67,446
|
-23%
|
|
