Compass Pathways
CMPS
168 hedge funds and large institutions have $379M invested in Compass Pathways in 2025 Q4 according to their latest regulatory filings, with 37 funds opening new positions, 38 increasing their positions, 39 reducing their positions, and 25 closing their positions.
229% more call options, than puts
Call options by funds: $20M | Put options by funds: $6.06M
48% more first-time investments, than exits
New positions opened: 37 | Existing positions closed: 25
25% more funds holding in top 10
Funds holding in top 10: 4 → 5 (+1)
19% more capital invested
Capital invested by funds: $318M → $379M (+$61.2M)
7% more funds holding
Funds holding: 157 → 168 (+11)
0.57% less ownership
Funds ownership: 57.83% → 57.25% (-0.57%)
3% less repeat investments, than reductions
Existing positions increased: 38 | Existing positions reduced: 39
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Toronto Dominion Bank
Toronto, Ontario,
Ontario, Canada
|
+$9.32M |
| 2 |
SL
Siren LLC
Greenwich,
Connecticut
|
+$6.1M |
| 3 |
Point72 Asset Management
Stamford,
Connecticut
|
+$5.15M |
| 4 |
D.E. Shaw & Co
New York
|
+$4.73M |
| 5 |
EHI
Eagle Health Investments
Greenwich,
Connecticut
|
+$3.56M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
TCM
Tang Capital Management
San Diego,
California
|
-$12.6M |
| 2 |
Millennium Management
New York
|
-$8.1M |
| 3 |
NCM
Nantahala Capital Management
New Canaan,
Connecticut
|
-$7.85M |
| 4 |
HSBC Holdings
London,
United Kingdom
|
-$7.19M |
| 5 |
ABG
Ally Bridge Group
New York
|
-$6.26M |
CMPS Hedge Fund Activity: Q4 2025 in Review
168 of the 8,267 institutional investors tracked by Wall St. Rank reported a position in Compass Pathways (CMPS) for Q4 2025, worth a combined $379M — up 19% from $318M a quarter earlier.
Buyers outnumbered sellers: 37 funds opened new CMPS positions and 25 closed out — a net gain of 12 holders — while 38 added to existing stakes and 39 trimmed.
The largest buyer was Toronto Dominion Bank, adding an estimated $9.32M. The largest seller was Tang Capital Management, exiting entirely with an estimated $12.6M sold.
- 168 institutional investors held Compass Pathways (CMPS) as of Q4 2025, up from 157 in Q3 2025.
- Funds reported $379M of Compass Pathways stock for Q4 2025, up 19% quarter-over-quarter.
- 37 funds opened new Compass Pathways positions in Q4 2025 and 25 closed out, a net change of +12 holders.
- The largest Compass Pathways buyer in Q4 2025 was Toronto Dominion Bank, an estimated $9.32M added.
- The largest Compass Pathways seller in Q4 2025 was Tang Capital Management, an estimated $12.6M sold.
Based on aggregated 13F filings for Q4 2025.