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CMPS

Compass Pathways

157 hedge funds and large institutions have $318M invested in Compass Pathways in 2025 Q3 according to their latest regulatory filings, with 38 funds opening new positions, 49 increasing their positions, 24 reducing their positions, and 19 closing their positions.

New
Increased
Maintained
Reduced
Closed

289% more call options, than puts

Call options by funds: $19.9M | Put options by funds: $5.12M

119% more capital invested

Capital invested by funds: $145M → $318M (+$173M)

104% more repeat investments, than reductions

Existing positions increased: 49 | Existing positions reduced: 24

100% more first-time investments, than exits

New positions opened: 38 | Existing positions closed: 19

33% more funds holding in top 10

Funds holding in top 10: 34 (+1)

12% more funds holding

Funds holding: 140157 (+17)

2.52% more ownership

Funds ownership: 55.31%57.83% (+2.5%)

Holders
157
Holders Change
+17
Holders Change %
+12.14%
% of All Funds
2.06%
Holding in Top 10
4
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+33.33%
% of All Funds
0.05%
New
38
Increased
49
Reduced
24
Closed
19
Calls
$19.9M
Puts
$5.12M
Net Calls
+$14.8M
Net Calls Change
+$10.8M
Name Holding Trade Value Shares
Change
Change in
Stake
RI
1
RTW Investments
New York
$49.9M +$2.18M +485,461 +6%
DTC
2
Deep Track Capital
Connecticut
$45M -$4.36M -971,359 -11%
GC
3
GMT Capital
Georgia
$16.3M +$4.78M +1,062,900 +60%
Millennium Management
4
Millennium Management
New York
$15.6M +$4.38M +974,090 +56%
TCM
5
Tang Capital Management
California
$12.6M +$4.04M +900,000 +69%
UBS Group
6
UBS Group
Switzerland
$12.3M +$2.09M +465,802 +28%
AIM
7
ARK Investment Management
Florida
$12.2M +$2.12M +471,897 +29%
NCM
8
Nantahala Capital Management
Connecticut
$9.91M -$11M -2,450,000 -59%
PHS
9
PFM Health Sciences
California
$9.53M -$523K -116,423 -7%
JFG
10
Jefferies Financial Group
New York
$7.89M +$6.19M +1,376,905 New
HSBC Holdings
11
HSBC Holdings
United Kingdom
$7.19M +$807K +179,599 +17%
Ameriprise
12
Ameriprise
Minnesota
$6.93M +$5.43M +1,208,784 New
ACM
13
Aisling Capital Management
New York
$6.87M
Two Sigma Investments
14
Two Sigma Investments
New York
$6.16M +$4.32M +960,685 +838%
Morgan Stanley
15
Morgan Stanley
New York
$5.9M +$3.44M +764,472 +288%
ABG
16
Ally Bridge Group
New York
$5.88M -$2.06M -458,618 -31%
Toronto Dominion Bank
17
Toronto Dominion Bank
Ontario, Canada
$5.73M +$2.25M +500,000 +100%
Renaissance Technologies
18
Renaissance Technologies
New York
$5.45M +$3.32M +738,400 +347%
EHI
19
Eagle Health Investments
Connecticut
$5.36M +$4.2M +935,450 New
DCM
20
DAFNA Capital Management
California
$4.65M
D.E. Shaw & Co
21
D.E. Shaw & Co
New York
$3.89M +$3.05M +678,792 New
CP
22
CenterBook Partners
Connecticut
$3.65M +$2.86M +636,155 New
BOCH
23
Blue Owl Capital Holdings
New York
$3.47M +$1.69M +375,000 +163%
Schroder Investment Management Group
24
Schroder Investment Management Group
United Kingdom
$3.35M +$116K +25,741 +5%
Two Sigma Advisers
25
Two Sigma Advisers
New York
$3.14M +$2.46M +548,500 New

CMPS Hedge Fund Activity: Q3 2025 in Review

157 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Compass Pathways (CMPS) for Q3 2025, worth a combined $318M — up 119% from $145M a quarter earlier.

Buyers outnumbered sellers: 38 funds opened new CMPS positions and 19 closed out — a net gain of 19 holders — while 49 added to existing stakes and 24 trimmed.

The largest buyer was Jefferies Financial Group, opening a new position worth an estimated $6.19M. The largest seller was Nantahala Capital Management, cutting an estimated $11M.

  • 157 institutional investors held Compass Pathways (CMPS) as of Q3 2025, up from 140 in Q2 2025.
  • Funds reported $318M of Compass Pathways stock for Q3 2025, up 119% quarter-over-quarter.
  • 38 funds opened new Compass Pathways positions in Q3 2025 and 19 closed out, a net change of +19 holders.
  • The largest Compass Pathways buyer in Q3 2025 was Jefferies Financial Group, an estimated $6.19M added.
  • The largest Compass Pathways seller in Q3 2025 was Nantahala Capital Management, an estimated $11M sold.

Based on aggregated 13F filings for Q3 2025.