|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$303M
|
+$246M
|
+5,249,038
|
+1,433%
|
|
|
2
|
|
$211M
|
–
|
–
|
–
|
|
|
3
|
|
$169M
|
+$20.3M
|
+433,120
|
+16%
|
|
|
4
|
Redmile Group
San Francisco,
California
|
$164M
|
+$1.46M
|
+31,217
|
+1%
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$123M
|
+$14.3M
|
+305,793
|
+16%
|
|
|
6
|
Wellington Management Group
Boston,
Massachusetts
|
$118M
|
+$10.2M
|
+217,353
|
+11%
|
|
|
7
|
State Street
Boston,
Massachusetts
|
$100M
|
-$11.1M
|
-237,100
|
-11%
|
|
|
8
|
RA Capital Management
Boston,
Massachusetts
|
$86.4M
|
+$75.1M
|
+1,600,000
|
New
|
|
|
9
|
Eventide Asset Management
Boston,
Massachusetts
|
$60.9M
|
-$46M
|
-980,908
|
-47%
|
|
|
10
|
|
$59.3M
|
-$6.68M
|
-142,436
|
-11%
|
|
|
11
|
Opaleye Management
Boston,
Massachusetts
|
$53M
|
–
|
–
|
–
|
|
|
12
|
Adage Capital Partners
Boston,
Massachusetts
|
$51.3M
|
-$40.8M
|
-868,478
|
-48%
|
|
|
13
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$47.4M
|
+$23M
|
+489,361
|
+126%
|
|
|
14
|
Geode Capital Management
Boston,
Massachusetts
|
$42.8M
|
+$5.61M
|
+119,559
|
+18%
|
|
|
15
|
Citadel Advisors
Miami,
Florida
|
$42.3M
|
+$19.3M
|
+411,890
|
+111%
|
|
|
16
|
Viking Global Investors
Stamford,
Connecticut
|
$41.2M
|
+$35.8M
|
+762,296
|
New
|
|
|
17
|
Octagon Capital Advisors
New York
|
$41.1M
|
+$9.38M
|
+200,000
|
+36%
|
|
|
18
|
Polar Capital Holdings
London,
United Kingdom
|
$39M
|
+$10.5M
|
+222,843
|
+45%
|
|
|
19
|
Cowen and Company
New York
|
$35.1M
|
+$29.1M
|
+620,883
|
+2,187%
|
|
|
20
|
Driehaus Capital Management
Chicago,
Illinois
|
$29.8M
|
-$1.61M
|
-34,246
|
-6%
|
|
|
21
|
|
$28.8M
|
+$4.86M
|
+103,578
|
+24%
|
|
|
22
|
Fred Alger Management
New York
|
$28.4M
|
+$24.7M
|
+525,867
|
New
|
|
|
23
|
Vivo Capital
Palo Alto,
California
|
$26.2M
|
-$22.7M
|
-484,453
|
-50%
|
|
|
24
|
Northern Trust
Chicago,
Illinois
|
$24.8M
|
+$2.2M
|
+46,850
|
+11%
|
|
|
25
|
|
$22.4M
|
+$19.4M
|
+414,300
|
New
|
|
