|
1
|
|
$131M
|
–
|
–
|
–
|
|
|
2
|
Redmile Group
San Francisco,
California
|
$101M
|
-$10.3M
|
-375,707
|
-11%
|
|
|
3
|
|
$90.3M
|
+$47.6M
|
+1,732,777
|
+179%
|
|
|
4
|
Eventide Asset Management
Boston,
Massachusetts
|
$70.5M
|
+$1.28M
|
+46,475
|
+2%
|
|
|
5
|
State Street
Boston,
Massachusetts
|
$70M
|
+$5.96M
|
+217,241
|
+12%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$65.9M
|
+$4.72M
|
+172,079
|
+10%
|
|
|
7
|
Wellington Management Group
Boston,
Massachusetts
|
$65.6M
|
+$2.04M
|
+74,263
|
+4%
|
|
|
8
|
Adage Capital Partners
Boston,
Massachusetts
|
$60.8M
|
-$2.24M
|
-81,522
|
-4%
|
|
|
9
|
|
$41.5M
|
–
|
–
|
–
|
|
|
10
|
Acuta Capital Partners
Redwood City,
California
|
$33M
|
-$827K
|
-30,118
|
-3%
|
|
|
11
|
Opaleye Management
Boston,
Massachusetts
|
$32.9M
|
–
|
–
|
–
|
|
|
12
|
Vivo Capital
Palo Alto,
California
|
$32.4M
|
-$8.87M
|
-322,969
|
-25%
|
|
|
13
|
Perceptive Advisors
New York
|
$24.8M
|
+$20.4M
|
+742,699
|
New
|
|
|
14
|
Geode Capital Management
Boston,
Massachusetts
|
$22.5M
|
+$8.79M
|
+320,251
|
+91%
|
|
|
15
|
Driehaus Capital Management
Chicago,
Illinois
|
$19.6M
|
+$6.49M
|
+236,471
|
+68%
|
|
|
16
|
Octagon Capital Advisors
New York
|
$18.8M
|
–
|
–
|
–
|
|
|
17
|
Polar Capital Holdings
London,
United Kingdom
|
$16.7M
|
–
|
–
|
–
|
|
|
18
|
Cresset Asset Management
Chicago,
Illinois
|
$15.3M
|
–
|
–
|
–
|
|
|
19
|
|
$14.4M
|
+$4.66M
|
+169,912
|
+65%
|
|
|
20
|
Northern Trust
Chicago,
Illinois
|
$13.8M
|
+$8.37M
|
+305,057
|
+285%
|
|
|
21
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$13.4M
|
+$1.52M
|
+55,546
|
+16%
|
|
|
22
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$13M
|
+$1.56M
|
+56,818
|
+17%
|
|
|
23
|
Citadel Advisors
Miami,
Florida
|
$12.4M
|
-$16.6M
|
-604,845
|
-62%
|
|
|
24
|
Fidelity Investments
Boston,
Massachusetts
|
$12.2M
|
+$779K
|
+28,395
|
+8%
|
|
|
25
|
Ikarian Capital
Dallas,
Texas
|
$12.2M
|
-$6.33M
|
-230,746
|
-39%
|
|
