|
1
|
Baker Bros. Advisors
New York
|
$904M
|
–
|
–
|
–
|
|
|
2
|
Avoro Capital Advisors
New York
|
$385M
|
+$28.8M
|
+263,889
|
+8%
|
|
|
3
|
Perceptive Advisors
New York
|
$357M
|
-$3.6M
|
-33,000
|
-1%
|
|
|
4
|
|
$347M
|
+$271M
|
+2,489,461
|
+452%
|
|
|
5
|
|
$309M
|
+$18.7M
|
+171,155
|
+7%
|
|
|
6
|
NEA Management Company
Timonium,
Maryland
|
$261M
|
-$136M
|
-1,250,000
|
-35%
|
|
|
7
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
$203M
|
+$194M
|
+1,782,894
|
New
|
|
|
8
|
Deerfield Management
New York
|
$196M
|
–
|
–
|
–
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$173M
|
-$13M
|
-118,982
|
-7%
|
|
|
10
|
|
$154M
|
-$5.81M
|
-53,255
|
-4%
|
|
|
11
|
Soleus Capital Management
Greenwich,
Connecticut
|
$147M
|
-$57.1M
|
-523,880
|
-29%
|
|
|
12
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$146M
|
+$4.31M
|
+39,535
|
+3%
|
|
|
13
|
Tang Capital Management
San Diego,
California
|
$120M
|
–
|
–
|
–
|
|
|
14
|
Geode Capital Management
Boston,
Massachusetts
|
$102M
|
+$6.58M
|
+60,386
|
+7%
|
|
|
15
|
Toronto Dominion Bank
Toronto, Ontario,
Ontario, Canada
|
$101M
|
+$96.3M
|
+882,758
|
New
|
|
|
16
|
|
$87.3M
|
+$12.2M
|
+112,148
|
+17%
|
|
|
17
|
Bank of America
Charlotte,
North Carolina
|
$81.5M
|
-$28.7M
|
-262,789
|
-27%
|
|
|
18
|
Apis Capital Advisors
New York
|
$58.8M
|
-$9.49M
|
-87,000
|
-14%
|
|
|
19
|
Nearwater Capital Markets
Dublin 4, Dublin,
Ireland
|
$54M
|
-$5.14M
|
-47,100
|
-9%
|
|
|
20
|
Artisan Partners
Milwaukee,
Wisconsin
|
$52.2M
|
-$9.77M
|
-89,571
|
-16%
|
|
|
21
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$50.1M
|
+$28.1M
|
+257,736
|
+142%
|
|
|
22
|
Wellington Management Group
Boston,
Massachusetts
|
$49M
|
+$6.3M
|
+57,813
|
+16%
|
|
|
23
|
AllianceBernstein
Nashville,
Tennessee
|
$46.3M
|
-$939K
|
-8,610
|
-2%
|
|
|
24
|
Holocene Advisors
New York
|
$42.2M
|
-$35.5M
|
-325,361
|
-47%
|
|
|
25
|
Sofinnova Investments
Menlo Park,
California
|
$41.8M
|
+$7.28M
|
+66,758
|
+22%
|
|
