|
1
|
Baker Bros. Advisors
New York
|
$391M
|
+$98.7M
|
+2,465,347
|
+45%
|
|
|
2
|
Perceptive Advisors
New York
|
$146M
|
+$53M
|
+1,323,111
|
+81%
|
|
|
3
|
|
$111M
|
+$7.04M
|
+175,764
|
+8%
|
|
|
4
|
NEA Management Company
Timonium,
Maryland
|
$106M
|
-$6M
|
-150,000
|
-7%
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$102M
|
+$15.7M
|
+391,262
|
+23%
|
|
|
6
|
|
$74.7M
|
+$29.2M
|
+728,773
|
+93%
|
|
|
7
|
Soleus Capital Management
Greenwich,
Connecticut
|
$58.2M
|
-$73.4M
|
-1,832,958
|
-61%
|
|
|
8
|
Tang Capital Management
San Diego,
California
|
$56.8M
|
+$46M
|
+1,150,000
|
New
|
|
|
9
|
Eventide Asset Management
Boston,
Massachusetts
|
$53.8M
|
-$12M
|
-300,628
|
-22%
|
|
|
10
|
UBS Group
Zurich,
Switzerland
|
$42.2M
|
+$30.8M
|
+769,891
|
+910%
|
|
|
11
|
Sio Capital Management
New York
|
$38.9M
|
+$31.5M
|
+786,526
|
New
|
|
|
12
|
Apis Capital Advisors
New York
|
$38.3M
|
+$31.1M
|
+776,000
|
New
|
|
|
13
|
Geode Capital Management
Boston,
Massachusetts
|
$37.9M
|
+$3.57M
|
+89,242
|
+13%
|
|
|
14
|
Deerfield Management
New York
|
$36.2M
|
+$29.4M
|
+733,530
|
New
|
|
|
15
|
State Street
Boston,
Massachusetts
|
$35.7M
|
+$5.42M
|
+135,396
|
+23%
|
|
|
16
|
BVF Inc
San Francisco,
California
|
$32.5M
|
-$112M
|
-2,807,579
|
-81%
|
|
|
17
|
AllianceBernstein
Nashville,
Tennessee
|
$32.2M
|
+$25M
|
+624,379
|
+2,209%
|
|
|
18
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$29.6M
|
+$23.3M
|
+582,970
|
+3,839%
|
|
|
19
|
Artisan Partners
Milwaukee,
Wisconsin
|
$28.9M
|
+$7.37M
|
+184,214
|
+46%
|
|
|
20
|
Bank of America
Charlotte,
North Carolina
|
$26.7M
|
+$11.1M
|
+276,653
|
+105%
|
|
|
21
|
Millennium Management
New York
|
$26M
|
+$17.5M
|
+437,566
|
+491%
|
|
|
22
|
Saturn V Capital Management
Austin,
Texas
|
$23.4M
|
-$28.5M
|
-711,692
|
-60%
|
|
|
23
|
|
$20.9M
|
+$14.8M
|
+370,461
|
+706%
|
|
|
24
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$19.3M
|
+$5.1M
|
+127,348
|
+48%
|
|
|
25
|
|
$18.4M
|
+$14.9M
|
+371,944
|
New
|
|
