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187 hedge funds and large institutions have $779M invested in CareDx in 2025 Q3 according to their latest regulatory filings, with 35 funds opening new positions, 62 increasing their positions, 64 reducing their positions, and 45 closing their positions.

New
Increased
Maintained
Reduced
Closed

44% more call options, than puts

Call options by funds: $2.11M | Put options by funds: $1.47M

25% more funds holding in top 10

Funds holding in top 10: 45 (+1)

3.23% more ownership

Funds ownership: 97.41%100.65% (+3.2%)

3% less repeat investments, than reductions

Existing positions increased: 62 | Existing positions reduced: 64

5% less funds holding

Funds holding: 197187 (-10)

22% less first-time investments, than exits

New positions opened: 35 | Existing positions closed: 45

26% less capital invested

Capital invested by funds: $1.05B → $779M (-$268M)

Holders
187
Holders Change
-10
Holders Change %
-5.08%
% of All Funds
2.45%
Holding in Top 10
5
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+25%
% of All Funds
0.07%
New
35
Increased
62
Reduced
64
Closed
45
Calls
$2.11M
Puts
$1.47M
Net Calls
+$640K
Net Calls Change
-$671K
Name Holding Trade Value Shares
Change
Change in
Stake
BlackRock
1
BlackRock
New York
$69.3M +$1.55M +108,998 +2%
Vanguard Group
2
Vanguard Group
Pennsylvania
$54.5M -$16.5M -1,160,864 -24%
BAMCO Inc
3
BAMCO Inc
New York
$45.9M +$10.3M +719,523 +30%
State Street
4
State Street
Massachusetts
$37.3M +$5.51M +386,304 +18%
OAM
5
Ophir Asset Management
Australia
$32M +$4.35M +304,953 +16%
DM
6
Deerfield Management
New York
$31.9M +$31.2M +2,191,000 New
B
7
Braidwell
Connecticut
$31.7M +$31.1M +2,182,781 New
AIM
8
ARK Investment Management
Florida
$31.6M +$1M +70,468 +3%
Sumitomo Mitsui Trust Group
9
Sumitomo Mitsui Trust Group
Japan
$25.3M +$7.17M +503,136 +41%
NAMA
10
Nikko Asset Management Americas
New York
$25.3M +$7.19M +504,473 +41%
GS
11
Gagnon Securities
New York
$25.1M +$2.57M +180,513 +12%
Geode Capital Management
12
Geode Capital Management
Massachusetts
$18.9M -$372K -26,072 -2%
Dimensional Fund Advisors
13
Dimensional Fund Advisors
Texas
$17.7M +$3.62M +253,739 +26%
Renaissance Technologies
14
Renaissance Technologies
New York
$16.8M -$1.43K -100 -0%
Connor, Clark & Lunn Investment Management (CC&L)
15
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$15.6M -$178K -12,499 -1%
ACH
16
ArrowMark Colorado Holdings
Colorado
$14.1M +$3.53M +247,709 +34%
PCM
17
Portolan Capital Management
Massachusetts
$13.6M +$4.33M +303,555 +48%
FAM
18
Fred Alger Management
New York
$13.5M -$4.34M -304,736 -25%
Goldman Sachs
19
Goldman Sachs
New York
$12.5M -$3.82M -268,292 -24%
Chevy Chase Trust
20
Chevy Chase Trust
Maryland
$10.8M +$3.3M +231,202 +45%
Jacobs Levy Equity Management
21
Jacobs Levy Equity Management
New Jersey
$10.2M -$5.54M -388,321 -36%
Citadel Advisors
22
Citadel Advisors
Florida
$9.07M -$2.38M -166,854 -21%
D.E. Shaw & Co
23
D.E. Shaw & Co
New York
$8.64M -$298K -20,883 -3%
ZDA
24
Zweig-DiMenna Associates
New York
$8.36M +$4.97M +348,400 +154%
BG
25
Bellevue Group
Switzerland
$8.33M -$2.56M -179,415 -24%

CDNA Hedge Fund Activity: Q3 2025 in Review

187 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in CareDx (CDNA) for Q3 2025, worth a combined $779M — down 26% from $1.05B a quarter earlier.

Sellers outnumbered buyers: 45 funds closed out of CDNA and 35 opened new positions — a net loss of 10 holders — while 64 trimmed existing stakes and 62 added.

The largest buyer was Deerfield Management, opening a new position worth an estimated $31.2M. The largest seller was Invesco, cutting an estimated $34.7M.

  • 187 institutional investors held CareDx (CDNA) as of Q3 2025, down from 197 in Q2 2025.
  • Funds reported $779M of CareDx stock for Q3 2025, down 26% quarter-over-quarter.
  • 35 funds opened new CareDx positions in Q3 2025 and 45 closed out, a net change of -10 holders.
  • The largest CareDx buyer in Q3 2025 was Deerfield Management, an estimated $31.2M added.
  • The largest CareDx seller in Q3 2025 was Invesco, an estimated $34.7M sold.

Based on aggregated 13F filings for Q3 2025.