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218 hedge funds and large institutions have $995M invested in CareDx in 2025 Q1 according to their latest regulatory filings, with 39 funds opening new positions, 65 increasing their positions, 81 reducing their positions, and 28 closing their positions.

New
Increased
Maintained
Reduced
Closed

67% more funds holding in top 10

Funds holding in top 10: 35 (+2)

39% more first-time investments, than exits

New positions opened: 39 | Existing positions closed: 28

4% more funds holding

Funds holding: 210218 (+8)

2.16% more ownership

Funds ownership: 98.9%101.06% (+2.2%)

12% less capital invested

Capital invested by funds: $1.14B → $995M (-$141M)

20% less repeat investments, than reductions

Existing positions increased: 65 | Existing positions reduced: 81

34% less call options, than puts

Call options by funds: $729K | Put options by funds: $1.11M

Holders
218
Holders Change
+8
Holders Change %
+3.81%
% of All Funds
2.92%
Holding in Top 10
5
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+66.67%
% of All Funds
0.07%
New
39
Increased
65
Reduced
81
Closed
28
Calls
$729K
Puts
$1.11M
Net Calls
-$380K
Net Calls Change
-$631K
Name Holding Trade Value Shares
Change
Change in
Stake
BlackRock
1
BlackRock
New York
$90.1M -$247K -11,469 -0.2%
Vanguard Group
2
Vanguard Group
Pennsylvania
$85.8M -$553K -25,659 -0.5%
Invesco
3
Invesco
Georgia
$47.4M +$24.8M +1,153,011 +76%
State Street
4
State Street
Massachusetts
$44.1M -$3.76M -174,499 -7%
AIM
5
ARK Investment Management
Florida
$41.7M -$1.33M -61,718 -3%
BAMCO Inc
6
BAMCO Inc
New York
$38.9M -$372K -17,293 -0.8%
OAM
7
Ophir Asset Management
Australia
$28.7M +$34.9M +1,618,369 New
HRCM
8
Hood River Capital Management
Florida
$28.1M +$34.1M +1,583,956 New
FAM
9
Fred Alger Management
New York
$25.5M -$3.86M -179,385 -11%
GS
10
Gagnon Securities
New York
$25.2M -$205K -9,507 -0.7%
Sumitomo Mitsui Trust Group
11
Sumitomo Mitsui Trust Group
Japan
$24.4M -$2.61M -121,264 -8%
NAMA
12
Nikko Asset Management Americas
New York
$24.4M -$2.61M -121,264 -8%
Geode Capital Management
13
Geode Capital Management
Massachusetts
$22.7M +$994K +46,160 +4%
Renaissance Technologies
14
Renaissance Technologies
New York
$22M -$4.2M -195,200 -14%
Jacobs Levy Equity Management
15
Jacobs Levy Equity Management
New Jersey
$20.2M -$2.23M -103,560 -8%
Goldman Sachs
16
Goldman Sachs
New York
$19.7M +$3.67M +170,504 +18%
Connor, Clark & Lunn Investment Management (CC&L)
17
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$17.8M +$2.77M +128,383 +15%
BG
18
Bellevue Group
Switzerland
$15.8M -$10.5M -485,409 -35%
Citadel Advisors
19
Citadel Advisors
Florida
$14.1M +$6.11M +283,768 +56%
D.E. Shaw & Co
20
D.E. Shaw & Co
New York
$13.9M -$7.89M -366,215 -32%
BWLSA
21
Blue Water Life Science Advisors
California
$12.9M +$2.58M +120,014 +20%
Dimensional Fund Advisors
22
Dimensional Fund Advisors
Texas
$12.3M -$1.1M -50,926 -7%
Russell Investments Group
23
Russell Investments Group
United Kingdom
$10.6M +$6.06M +281,592 +90%
Macquarie Group
24
Macquarie Group
Australia
$9.97M +$2.6M +120,632 +27%
Chevy Chase Trust
25
Chevy Chase Trust
Maryland
$9.5M +$11.5M +535,341 New

CDNA Hedge Fund Activity: Q1 2025 in Review

218 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in CareDx (CDNA) for Q1 2025, worth a combined $995M — down 12% from $1.14B a quarter earlier.

Buyers outnumbered sellers: 39 funds opened new CDNA positions and 28 closed out — a net gain of 11 holders — while 65 added to existing stakes and 81 trimmed.

The largest buyer was Ophir Asset Management, opening a new position worth an estimated $34.9M. The largest seller was Millennium Management, cutting an estimated $11.2M.

  • 218 institutional investors held CareDx (CDNA) as of Q1 2025, up from 210 in Q4 2024.
  • Funds reported $995M of CareDx stock for Q1 2025, down 12% quarter-over-quarter.
  • 39 funds opened new CareDx positions in Q1 2025 and 28 closed out, a net change of +11 holders.
  • The largest CareDx buyer in Q1 2025 was Ophir Asset Management, an estimated $34.9M added.
  • The largest CareDx seller in Q1 2025 was Millennium Management, an estimated $11.2M sold.

Based on aggregated 13F filings for Q1 2025.