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187 hedge funds and large institutions have $779M invested in CareDx in 2025 Q3 according to their latest regulatory filings, with 35 funds opening new positions, 62 increasing their positions, 64 reducing their positions, and 45 closing their positions.

New
Increased
Maintained
Reduced
Closed

44% more call options, than puts

Call options by funds: $2.11M | Put options by funds: $1.47M

25% more funds holding in top 10

Funds holding in top 10: 45 (+1)

3.23% more ownership

Funds ownership: 97.41%100.65% (+3.2%)

3% less repeat investments, than reductions

Existing positions increased: 62 | Existing positions reduced: 64

5% less funds holding

Funds holding: 197187 (-10)

22% less first-time investments, than exits

New positions opened: 35 | Existing positions closed: 45

26% less capital invested

Capital invested by funds: $1.05B → $779M (-$268M)

Holders
187
Holders Change
-10
Holders Change %
-5.08%
% of All Funds
2.45%
Holding in Top 10
5
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+25%
% of All Funds
0.07%
New
35
Increased
62
Reduced
64
Closed
45
Calls
$2.11M
Puts
$1.47M
Net Calls
+$640K
Net Calls Change
-$671K
Name Holding Trade Value Shares
Change
Change in
Stake
LPL Financial
101
LPL Financial
California
$325K -$182K -12,753 -36%
Janus Henderson Group
102
Janus Henderson Group
United Kingdom
$318K
Zurich Cantonal Bank
103
Zurich Cantonal Bank
Switzerland
$316K +$73.4K +5,151 +31%
IIM
104
INTECH Investment Management
Florida
$310K -$98.5K -6,907 -24%
AACP
105
Advantage Alpha Capital Partners
California
$308K +$302K +21,164 New
Citigroup
106
Citigroup
New York
$298K -$215K -15,062 -42%
Janney Montgomery Scott
107
Janney Montgomery Scott
Pennsylvania
$295K -$12K -840 -4%
PA
108
Profund Advisors
Maryland
$292K +$69.6K +4,884 +32%
FGP
109
Freestone Grove Partners
California
$286K +$281K +19,678 New
State Board of Administration of Florida Retirement System
110
State Board of Administration of Florida Retirement System
Florida
$272K
Manulife (Manufacturers Life Insurance)
111
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$262K -$139K -9,716 -35%
Allspring Global Investments
112
Allspring Global Investments
North Carolina
$261K -$4.66M -327,035 -95%
VRS
113
Virginia Retirement Systems
Virginia
$253K -$8.55K -600 -3%
Envestnet Asset Management
114
Envestnet Asset Management
Illinois
$247K -$78.2K -5,488 -24%
PNC Financial Services Group
115
PNC Financial Services Group
Pennsylvania
$240K +$68.2K +4,787 +41%
New York State Common Retirement Fund
116
New York State Common Retirement Fund
New York
$238K -$915K -64,175 -80%
Canada Life
117
Canada Life
Manitoba, Canada
$234K
HHAA
118
Henry H. Armstrong Associates
Pennsylvania
$233K
ASRS
119
Arizona State Retirement System
Arizona
$227K +$4.11K +288 +2%
PFSRSONJ
120
Police & Firemen's Retirement System of New Jersey
New Jersey
$219K +$45.2K +3,172 +27%
Royal Bank of Canada
121
Royal Bank of Canada
Ontario, Canada
$216K -$650K -45,618 -75%
SG Americas Securities
122
SG Americas Securities
New York
$201K +$197K +13,834 New
EWM
123
Empirical Wealth Management
Washington
$190K
Teacher Retirement System of Texas
124
Teacher Retirement System of Texas
Texas
$189K -$17.3K -1,213 -9%
EC
125
EntryPoint Capital
New York
$188K +$184K +12,940 New

CDNA Hedge Fund Activity: Q3 2025 in Review

187 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in CareDx (CDNA) for Q3 2025, worth a combined $779M — down 26% from $1.05B a quarter earlier.

Sellers outnumbered buyers: 45 funds closed out of CDNA and 35 opened new positions — a net loss of 10 holders — while 64 trimmed existing stakes and 62 added.

The largest buyer was Deerfield Management, opening a new position worth an estimated $31.2M. The largest seller was Invesco, cutting an estimated $34.7M.

  • 187 institutional investors held CareDx (CDNA) as of Q3 2025, down from 197 in Q2 2025.
  • Funds reported $779M of CareDx stock for Q3 2025, down 26% quarter-over-quarter.
  • 35 funds opened new CareDx positions in Q3 2025 and 45 closed out, a net change of -10 holders.
  • The largest CareDx buyer in Q3 2025 was Deerfield Management, an estimated $31.2M added.
  • The largest CareDx seller in Q3 2025 was Invesco, an estimated $34.7M sold.

Based on aggregated 13F filings for Q3 2025.