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C4 Therapeutics

123 hedge funds and large institutions have $221M invested in C4 Therapeutics in 2026 Q1 according to their latest regulatory filings, with 34 funds opening new positions, 41 increasing their positions, 31 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed

209% more first-time investments, than exits

New positions opened: 34 | Existing positions closed: 11

189% more call options, than puts

Call options by funds: $1.02M | Put options by funds: $352K

45% more capital invested

Capital invested by funds: $153M → $221M (+$68.8M)

32% more repeat investments, than reductions

Existing positions increased: 41 | Existing positions reduced: 31

22% more funds holding

Funds holding: 101123 (+22)

4.2% more ownership

Funds ownership: 82.39%86.59% (+4.2%)

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

Holders
123
Holders Change
+22
Holders Change %
+21.78%
% of All Funds
1.51%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
34
Increased
41
Reduced
31
Closed
11
Calls
$1.02M
Puts
$352K
Net Calls
+$666K
Net Calls Change
+$80K
Name Holding Trade Value Shares
Change
Change in
Stake
DC
76
Diametric Capital
Massachusetts
$91K +$81.5K +34,594 New
VGA
77
Vanguard Global Advisers
Pennsylvania
$89K +$79.7K +33,832 New
PCM
78
Prelude Capital Management
New York
$81.4K +$72.9K +30,957 New
FCM
79
Farallon Capital Management
California
$73.6K
JFG
80
Jefferies Financial Group
New York
$68.7K -$21.7K -9,220 -26%
CFM
81
Catalyst Funds Management
Australia
$67.7K -$39.5K -16,760 -39%
SEI Investments
82
SEI Investments
Pennsylvania
$66.1K +$59.2K +25,134 New
CAM
83
Cresset Asset Management
Illinois
$65.8K
WG
84
Winton Group
United Kingdom
$65K +$58.2K +24,700 New
SSA
85
Schonfeld Strategic Advisors
New York
$63K +$56.4K +23,944 New
GCM
86
Graham Capital Management
Connecticut
$62.4K -$185K -78,465 -77%
Corient Private Wealth
87
Corient Private Wealth
Florida
$56.2K -$50.4K -21,387 -50%
CFO
88
Callan Family Office
Pennsylvania
$50.4K -$29.7K -12,597 -40%
CUAMC
89
China Universal Asset Management Company
China
$45.5K +$3.59K +1,524 +10%
Prudential Financial
90
Prudential Financial
New Jersey
$41.9K +$2.12K +900 +6%
VPIM
91
Vanguard Personalized Indexing Management
California
$40.1K +$59 +25 +0.2%
DIG
92
Dauntless Investment Group
New Hampshire
$39.5K +$35.3K +15,000 New
EL
93
EWA LLC
Pennsylvania
$38.3K -$5.46K -2,317 -14%
NMC
94
Nine Masts Capital
Hong Kong
$37.2K +$6.32K +2,685 +23%
HSBC Holdings
95
HSBC Holdings
United Kingdom
$36K
NLA
96
Northern Lights Advisors
Washington
$34K
CAS
97
CTC Alternative Strategies
Illinois
$28.4K +$25.4K +10,792 New
SC
98
SummitTX Capital
Texas
$27.5K +$24.6K +10,466 New
TSS
99
Two Sigma Securities
New York
$26.8K +$24K +10,203 New
SW
100
Simplicity Wealth
New Jersey
$26.8K -$2 -1 -0%

CCCC Hedge Fund Activity: Q1 2026 in Review

123 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in C4 Therapeutics (CCCC) for Q1 2026, worth a combined $221M — up 45% from $153M a quarter earlier.

Buyers outnumbered sellers: 34 funds opened new CCCC positions and 11 closed out — a net gain of 23 holders — while 41 added to existing stakes and 31 trimmed.

The largest buyer was JP Morgan Chase, adding an estimated $7.58M. The largest seller was Point72 Asset Management, cutting an estimated $21.8M.

  • 123 institutional investors held C4 Therapeutics (CCCC) as of Q1 2026, up from 101 in Q4 2025.
  • Funds reported $221M of C4 Therapeutics stock for Q1 2026, up 45% quarter-over-quarter.
  • 34 funds opened new C4 Therapeutics positions in Q1 2026 and 11 closed out, a net change of +23 holders.
  • The largest C4 Therapeutics buyer in Q1 2026 was JP Morgan Chase, an estimated $7.58M added.
  • The largest C4 Therapeutics seller in Q1 2026 was Point72 Asset Management, an estimated $21.8M sold.

Based on aggregated 13F filings for Q1 2026.