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C4 Therapeutics

123 hedge funds and large institutions have $221M invested in C4 Therapeutics in 2026 Q1 according to their latest regulatory filings, with 34 funds opening new positions, 41 increasing their positions, 31 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed

209% more first-time investments, than exits

New positions opened: 34 | Existing positions closed: 11

189% more call options, than puts

Call options by funds: $1.02M | Put options by funds: $352K

45% more capital invested

Capital invested by funds: $153M → $221M (+$68.8M)

32% more repeat investments, than reductions

Existing positions increased: 41 | Existing positions reduced: 31

22% more funds holding

Funds holding: 101123 (+22)

4.2% more ownership

Funds ownership: 82.39%86.59% (+4.2%)

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

Holders
123
Holders Change
+22
Holders Change %
+21.78%
% of All Funds
1.51%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
34
Increased
41
Reduced
31
Closed
11
Calls
$1.02M
Puts
$352K
Net Calls
+$666K
Net Calls Change
+$80K
Name Holding Trade Value Shares
Change
Change in
Stake
Qube Research & Technologies (QRT)
26
Qube Research & Technologies (QRT)
United Kingdom
$1.98M +$1.09M +461,880 +159%
VFT
27
Vanguard Fiduciary Trust
Pennsylvania
$1.27M +$1.14M +484,131 New
SC
28
Stempoint Capital
New York
$1.19M +$1.07M +453,236 New
Charles Schwab
29
Charles Schwab
California
$1.19M +$6.58K +2,796 +0.6%
Dimensional Fund Advisors
30
Dimensional Fund Advisors
Texas
$1.16M +$344K +146,038 +49%
PIM
31
Platinum Investment Management
Australia
$1.01M +$906K +384,766 New
State Street
32
State Street
Massachusetts
$1.01M +$94.7K +40,200 +12%
Barclays
33
Barclays
United Kingdom
$836K +$232K +98,673 +45%
6CM
34
683 Capital Management
New York
$789K -$235K -100,000 -25%
Connor, Clark & Lunn Investment Management (CC&L)
35
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$729K +$564K +239,462 +635%
Fidelity Investments
36
Fidelity Investments
Massachusetts
$716K +$42.3K +17,962 +7%
Jacobs Levy Equity Management
37
Jacobs Levy Equity Management
New Jersey
$696K +$623K +264,620 New
SPS
38
Susquehanna Portfolio Strategies
Pennsylvania
$685K -$27.7K -11,774 -4%
Man Group
39
Man Group
United Kingdom
$675K +$236K +100,370 +64%
LPL Financial
40
LPL Financial
California
$649K +$8.23K +3,495 +1%
Invesco
41
Invesco
Georgia
$643K -$56.1K -23,843 -9%
Walleye Capital
42
Walleye Capital
New York
$629K -$481K -204,223 -46%
HWAM
43
Hennion & Walsh Asset Management
New Jersey
$587K -$32.9K -13,969 -6%
UBS Group
44
UBS Group
Switzerland
$568K +$384K +163,125 +309%
BNP Paribas Financial Markets
45
BNP Paribas Financial Markets
France
$501K +$443K +188,187 +8,708%
Northern Trust
46
Northern Trust
Illinois
$498K +$54.8K +23,272 +14%
Toronto Dominion Bank
47
Toronto Dominion Bank
Ontario, Canada
$459K +$411K +174,663 New
Point72 Asset Management
48
Point72 Asset Management
Connecticut
$445K -$21.8M -9,270,232 -98%
HF
49
HRT Financial
New York
$428K +$384K +162,930 New
Marshall Wace
50
Marshall Wace
United Kingdom
$409K -$258K -109,532 -41%

CCCC Hedge Fund Activity: Q1 2026 in Review

123 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in C4 Therapeutics (CCCC) for Q1 2026, worth a combined $221M — up 45% from $153M a quarter earlier.

Buyers outnumbered sellers: 34 funds opened new CCCC positions and 11 closed out — a net gain of 23 holders — while 41 added to existing stakes and 31 trimmed.

The largest buyer was JP Morgan Chase, adding an estimated $7.58M. The largest seller was Point72 Asset Management, cutting an estimated $21.8M.

  • 123 institutional investors held C4 Therapeutics (CCCC) as of Q1 2026, up from 101 in Q4 2025.
  • Funds reported $221M of C4 Therapeutics stock for Q1 2026, up 45% quarter-over-quarter.
  • 34 funds opened new C4 Therapeutics positions in Q1 2026 and 11 closed out, a net change of +23 holders.
  • The largest C4 Therapeutics buyer in Q1 2026 was JP Morgan Chase, an estimated $7.58M added.
  • The largest C4 Therapeutics seller in Q1 2026 was Point72 Asset Management, an estimated $21.8M sold.

Based on aggregated 13F filings for Q1 2026.