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C4 Therapeutics

97 hedge funds and large institutions have $117M invested in C4 Therapeutics in 2025 Q3 according to their latest regulatory filings, with 21 funds opening new positions, 26 increasing their positions, 38 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

49% more capital invested

Capital invested by funds: $78.2M → $117M (+$38.4M)

25% more call options, than puts

Call options by funds: $806K | Put options by funds: $645K

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

3.2% less ownership

Funds ownership: 77.02%73.82% (-3.2%)

5% less funds holding

Funds holding: 10297 (-5)

19% less first-time investments, than exits

New positions opened: 21 | Existing positions closed: 26

32% less repeat investments, than reductions

Existing positions increased: 26 | Existing positions reduced: 38

Holders
97
Holders Change
-5
Holders Change %
-4.9%
% of All Funds
1.27%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
21
Increased
26
Reduced
38
Closed
26
Calls
$806K
Puts
$645K
Net Calls
+$161K
Net Calls Change
+$64K
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
26
Fidelity Investments
Massachusetts
$469K +$24K +9,990 +5%
HWAM
27
Hennion & Walsh Asset Management
New Jersey
$455K -$8.96K -3,733 -2%
ACH
28
ArrowMark Colorado Holdings
Colorado
$454K
Jane Street
29
Jane Street
New York
$452K -$694K -289,044 -59%
LPL Financial
30
LPL Financial
California
$446K +$11.2K +4,675 +2%
Invesco
31
Invesco
Georgia
$426K +$88.3K +36,803 +24%
Royal Bank of Canada
32
Royal Bank of Canada
Ontario, Canada
$405K -$135K -56,317 -24%
XT
33
XTX Topco
Cayman Islands
$333K +$100K +41,684 +38%
CSS
34
Cubist Systematic Strategies
Connecticut
$308K -$243K -101,302 -42%
Northern Trust
35
Northern Trust
Illinois
$307K -$3.25K -1,354 -1%
Mariner
36
Mariner
Kansas
$285K -$10.9K -4,528 -3%
Acadian Asset Management
37
Acadian Asset Management
Massachusetts
$282K -$27.9K -11,615 -8%
Qube Research & Technologies (QRT)
38
Qube Research & Technologies (QRT)
United Kingdom
$257K +$278K +115,973 New
AG
39
Algert Global
California
$236K +$255K +106,300 New
Marshall Wace
40
Marshall Wace
United Kingdom
$236K +$255K +106,275 New
Man Group
41
Man Group
United Kingdom
$200K +$28.3K +11,791 +15%
VIG
42
Vienna Insurance Group
Poland
$189K
SOW
43
State of Wyoming
Wyoming
$183K +$198K +82,509 New
BNP Paribas Financial Markets
44
BNP Paribas Financial Markets
France
$179K -$301K -125,371 -61%
BCM
45
Bridgeway Capital Management
Texas
$177K -$60K -25,000 -24%
IFO
46
Intrepid Family Office
Florida
$155K +$72K +30,000 +75%
SFI
47
Susquehanna Fundamental Investments
Pennsylvania
$150K
CAG
48
Crestwood Advisors Group
Massachusetts
$148K +$90.1K +37,536 +129%
UBS Group
49
UBS Group
Switzerland
$137K -$1.23M -510,376 -89%
Barclays
50
Barclays
United Kingdom
$95.6K -$6.63K -2,761 -6%

CCCC Hedge Fund Activity: Q3 2025 in Review

97 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in C4 Therapeutics (CCCC) for Q3 2025, worth a combined $117M — up 49% from $78.2M a quarter earlier.

Sellers outnumbered buyers: 26 funds closed out of CCCC and 21 opened new positions — a net loss of 5 holders — while 38 trimmed existing stakes and 26 added.

The largest buyer was Silverarc Capital Management, opening a new position worth an estimated $4.55M. The largest seller was Wasatch Advisors, cutting an estimated $6.17M.

  • 97 institutional investors held C4 Therapeutics (CCCC) as of Q3 2025, down from 102 in Q2 2025.
  • Funds reported $117M of C4 Therapeutics stock for Q3 2025, up 49% quarter-over-quarter.
  • 21 funds opened new C4 Therapeutics positions in Q3 2025 and 26 closed out, a net change of -5 holders.
  • The largest C4 Therapeutics buyer in Q3 2025 was Silverarc Capital Management, an estimated $4.55M added.
  • The largest C4 Therapeutics seller in Q3 2025 was Wasatch Advisors, an estimated $6.17M sold.

Based on aggregated 13F filings for Q3 2025.