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C4 Therapeutics

114 hedge funds and large institutions have $103M invested in C4 Therapeutics in 2025 Q1 according to their latest regulatory filings, with 26 funds opening new positions, 39 increasing their positions, 29 reducing their positions, and 23 closing their positions.

New
Increased
Maintained
Reduced
Closed

3,075% more call options, than puts

Call options by funds: $127K | Put options by funds: $4K

34% more repeat investments, than reductions

Existing positions increased: 39 | Existing positions reduced: 29

13% more first-time investments, than exits

New positions opened: 26 | Existing positions closed: 23

1% more funds holding

Funds holding: 113114 (+1)

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

0.94% less ownership

Funds ownership: 91.23%90.3% (-0.94%)

56% less capital invested

Capital invested by funds: $232M → $103M (-$129M)

Holders
114
Holders Change
+1
Holders Change %
+0.88%
% of All Funds
1.53%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
26
Increased
39
Reduced
29
Closed
23
Calls
$127K
Puts
$4K
Net Calls
+$123K
Net Calls Change
-$1.8M
Name Holding Trade Value Shares
Change
Change in
Stake
SG Americas Securities
26
SG Americas Securities
New York
$680K +$1.27M +425,096 New
AI
27
Atom Investors
Texas
$430K +$499K +167,148 +164%
Point72 Asset Management
28
Point72 Asset Management
Connecticut
$379K +$120K +40,389 +21%
HWAM
29
Hennion & Walsh Asset Management
New Jersey
$349K -$26.1K -8,736 -4%
Renaissance Technologies
30
Renaissance Technologies
New York
$343K +$640K +214,500 New
SFI
31
Susquehanna Fundamental Investments
Pennsylvania
$339K +$308K +103,339 +95%
LPL Financial
32
LPL Financial
California
$310K +$369K +123,585 +176%
Fidelity Investments
33
Fidelity Investments
Massachusetts
$310K -$73.4K -24,615 -11%
N
34
Nuveen
North Carolina
$308K
Mariner
35
Mariner
Kansas
$289K +$37K +12,397 +7%
American Century Companies
36
American Century Companies
Missouri
$227K +$27.3K +9,154 +7%
Bank of New York Mellon
37
Bank of New York Mellon
New York
$226K +$600 +201 +0.1%
AQR Capital Management
38
AQR Capital Management
Connecticut
$225K +$380K +127,244 +958%
Invesco
39
Invesco
Georgia
$223K +$210K +70,293 +102%
BCM
40
Bridgeway Capital Management
Texas
$208K +$387K +129,900 New
Barclays
41
Barclays
United Kingdom
$172K -$44.3K -14,845 -12%
SC
42
Shay Capital
New York
$149K +$279K +93,413 New
RhumbLine Advisers
43
RhumbLine Advisers
Massachusetts
$143K -$31K -10,382 -10%
OAM
44
Oxford Asset Management
United Kingdom
$138K +$257K +86,224 New
Man Group
45
Man Group
United Kingdom
$137K +$255K +85,623 New
VIG
46
Vienna Insurance Group
Poland
$136K
D.E. Shaw & Co
47
D.E. Shaw & Co
New York
$127K +$8.34K +2,796 +4%
Susquehanna International Group
48
Susquehanna International Group
Pennsylvania
$118K +$88.2K +29,559 +67%
Millennium Management
49
Millennium Management
New York
$105K -$878K -294,228 -82%
IIM
50
INTECH Investment Management
Florida
$85.8K +$70K +23,456 +78%

CCCC Hedge Fund Activity: Q1 2025 in Review

114 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in C4 Therapeutics (CCCC) for Q1 2025, worth a combined $103M — down 56% from $232M a quarter earlier.

Buyers outnumbered sellers: 26 funds opened new CCCC positions and 23 closed out — a net gain of 3 holders — while 39 added to existing stakes and 29 trimmed.

The largest buyer was OrbiMed, adding an estimated $7.31M. The largest seller was RA Capital Management, exiting entirely with an estimated $17.6M sold.

  • 114 institutional investors held C4 Therapeutics (CCCC) as of Q1 2025, up from 113 in Q4 2024.
  • Funds reported $103M of C4 Therapeutics stock for Q1 2025, down 56% quarter-over-quarter.
  • 26 funds opened new C4 Therapeutics positions in Q1 2025 and 23 closed out, a net change of +3 holders.
  • The largest C4 Therapeutics buyer in Q1 2025 was OrbiMed, an estimated $7.31M added.
  • The largest C4 Therapeutics seller in Q1 2025 was RA Capital Management, an estimated $17.6M sold.

Based on aggregated 13F filings for Q1 2025.