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C4 Therapeutics
CCCC

Overview Fund Activity

114 hedge funds and large institutions have $103M invested in C4 Therapeutics in 2025 Q1 according to their latest regulatory filings, with 27 funds opening new positions, 39 increasing their positions, 29 reducing their positions, and 23 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
114
Holders Change
+1
Holders Change %
+0.88%
% of All Funds
1.55%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
27
Increased
39
Reduced
29
Closed
23
Calls
$127K
Puts
$4K
Net Calls
+$123K
Net Calls Change
-$1.8M

Top Buyers

1
O
OrbiMed
New York
$10.9M
2
Jacobs Levy Equity Management
Jacobs Levy Equity Management
New Jersey
$1.12M
3
WA
Wasatch Advisors
Utah
$10.8M
4
Wells Fargo
Wells Fargo
California
$838K
5
SG Americas Securities
SG Americas Securities
New York
$680K

Top Sellers

1
RCM
RA Capital Management
Massachusetts
$0
2
Wellington Management Group
Wellington Management Group
Massachusetts
$0
3
SCM
Sio Capital Management
New York
$0
4
SCM
Silverarc Capital Management
Massachusetts
$1.41M
5
M&T Bank
M&T Bank
New York
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
SG Americas Securities
26
SG Americas Securities
New York
$680K +$680K +425,096 New
AI
27
Atom Investors
Texas
$430K +$267K +167,148 +164%
Point72 Asset Management
28
Point72 Asset Management
Connecticut
$379K +$64.6K +40,389 +21%
HWAM
29
Hennion & Walsh Asset Management
New Jersey
$349K -$14K -8,736 -4%
Renaissance Technologies
30
Renaissance Technologies
New York
$343K +$343K +214,500 New
SFI
31
Susquehanna Fundamental Investments
Pennsylvania
$339K +$165K +103,339 +95%
LPL Financial
32
LPL Financial
California
$310K +$198K +123,585 +176%
Fidelity Investments
33
Fidelity Investments
Massachusetts
$310K -$39.4K -24,615 -11%
NL
34
Nuveen LLC
North Carolina
$308K +$308K +192,424 New
Mariner
35
Mariner
Kansas
$289K +$19.9K +12,397 +7%
American Century Companies
36
American Century Companies
Missouri
$227K +$14.6K +9,154 +7%
Bank of New York Mellon
37
Bank of New York Mellon
New York
$226K +$322 +201 +0.1%
AQR Capital Management
38
AQR Capital Management
Connecticut
$225K +$204K +127,244 +958%
Invesco
39
Invesco
Georgia
$223K +$112K +70,293 +102%
BCM
40
Bridgeway Capital Management
Texas
$208K +$208K +129,900 New
Barclays
41
Barclays
United Kingdom
$172K -$23.7K -14,845 -12%
SC
42
Shay Capital
New York
$149K +$149K +93,413 New
RhumbLine Advisers
43
RhumbLine Advisers
Massachusetts
$143K -$16.6K -10,382 -10%
OAM
44
Oxford Asset Management
United Kingdom
$138K +$138K +86,224 New
Man Group
45
Man Group
United Kingdom
$137K +$137K +85,623 New
VIG
46
Vienna Insurance Group
Poland
$136K – – –
D.E. Shaw & Co
47
D.E. Shaw & Co
New York
$127K +$4.47K +2,796 +4%
Susquehanna International Group
48
Susquehanna International Group
Pennsylvania
$118K +$47.3K +29,559 +67%
Millennium Management
49
Millennium Management
New York
$105K -$471K -294,228 -82%
IIM
50
INTECH Investment Management
Florida
$85.8K +$37.5K +23,456 +78%
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