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CAI

Caris Life Sciences

186 hedge funds and large institutions have $3.92B invested in Caris Life Sciences in 2025 Q4 according to their latest regulatory filings, with 77 funds opening new positions, 63 increasing their positions, 30 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

185% more first-time investments, than exits

New positions opened: 77 | Existing positions closed: 27

184% more call options, than puts

Call options by funds: $14.4M | Put options by funds: $5.09M

110% more repeat investments, than reductions

Existing positions increased: 63 | Existing positions reduced: 30

40% more funds holding in top 10

Funds holding in top 10: 57 (+2)

35% more funds holding

Funds holding: 138186 (+48)

15% more capital invested

Capital invested by funds: $3.41B → $3.92B (+$507M)

11.18% more ownership

Funds ownership: 40.33%51.5% (+11%)

Holders
186
Holders Change
+48
Holders Change %
+34.78%
% of All Funds
2.26%
Holding in Top 10
7
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+40%
% of All Funds
0.09%
New
77
Increased
63
Reduced
30
Closed
27
Calls
$14.4M
Puts
$5.09M
Net Calls
+$9.35M
Net Calls Change
-$1.32M
Name Holding Trade Value Shares
Change
Change in
Stake
JHWEPV
1
J. H. Whitney Equity Partners VI
Connecticut
$547M +$571M +20,256,615 New
SSP
2
Sixth Street Partners
Texas
$523M -$141M -5,000,000 -21%
Fidelity Investments
3
Fidelity Investments
Massachusetts
$384M +$129M +4,584,333 +48%
Coatue Management
4
Coatue Management
New York
$265M -$9.07M -322,206 -3%
T. Rowe Price Investment Management
5
T. Rowe Price Investment Management
Maryland
$248M +$33.2M +1,180,200 +15%
B
6
Braidwell
Connecticut
$211M +$14.1M +500,000 +7%
PC
7
PointState Capital
New York
$181M +$79.8M +2,834,986 +73%
T. Rowe Price Associates
8
T. Rowe Price Associates
Maryland
$130M -$59.1M -2,096,780 -30%
Neuberger Berman Group
9
Neuberger Berman Group
New York
$103M -$15.3M -544,120 -13%
Millennium Management
10
Millennium Management
New York
$98.5M -$8.04M -285,425 -7%
O
11
OrbiMed
New York
$84.1M +$2.29M +81,153 +3%
Citadel Advisors
12
Citadel Advisors
Florida
$84M +$87.7M +3,113,956 New
JP Morgan Chase
13
JP Morgan Chase
New York
$66M +$44.7M +1,587,176 +185%
BlackRock
14
BlackRock
New York
$64M +$48.6M +1,724,155 +266%
UBS Group
15
UBS Group
Switzerland
$58.9M +$54.9M +1,948,107 +826%
Point72 Asset Management
16
Point72 Asset Management
Connecticut
$50.3M +$45.6M +1,618,236 +656%
Morgan Stanley
17
Morgan Stanley
New York
$48.4M +$7.34M +260,568 +17%
Balyasny Asset Management
18
Balyasny Asset Management
Illinois
$44.8M +$46.6M +1,653,363 +23,903%
LP
19
Longaeva Partners
Illinois
$40.7M +$6.3M +223,777 +17%
Ameriprise
20
Ameriprise
Minnesota
$40.6M -$4.91M -174,388 -10%
UBS AM
21
UBS AM
Illinois
$39.7M +$9.97M +354,104 +32%
Canada Pension Plan Investment Board
22
Canada Pension Plan Investment Board
Ontario, Canada
$39.5M +$3.99M +141,806 +11%
ClearBridge Investments
23
ClearBridge Investments
New York
$38.2M +$985K +34,977 +3%
PA
24
Perceptive Advisors
New York
$30.7M +$1.07M +38,043 +3%
Fidelity International
25
Fidelity International
Bermuda
$30.3M +$25.3M +896,855 +397%